Oncology
President Barack Obama yesterday detailed his support for "government-run insurance program that would compete with private insurers," CQ Politics reports.
A new study finds the average wait for a medical appointment has increased by more than a week since 2004, to 8.6 days, USA Today reports. In Boston, the worst-performing city of the 15 surveyed for the Merritt Hawkins and Associates study, patients waited nearly 50 days, on average, to see a doctor.
Health Care Crippling The Economy - Chicago Tribune
A Johnson & Johnson-run study found that its experimental drug TMC207 could make conventional tuberculosis treatment five times more effective against multi-drug resistant TB (MDR-TB) because it cleared traces of the TB bacteria in the sputum of 48 percent of study volunteers after eight weeks, Reuters reports (Emery, Reuters, 6/3). The results were published on Wednesday in the New England Journal of Medicine.
A combination of measures taken to improve nutrition, indoor air pollution, immunization and child pneumonia case management could reduce total child mortality worldwide by 17 percent and global pneumonia deaths by more than 90 percent, according to a study published in the June issue of the Bulletin of the World Health Organization, UPI reports.
During the warmer months, the use of trampolines is more frequent and as a result children are more likely to be hospitalized with related injuries, especially after bouncing with adults at the same time, according to doctors" warnings.
The Planned Parenthood Center of El Paso has begun to refocus its services on family planning and women"s health, and likely will shift its HIV/AIDS support programs to other providers that specialize in such services, according to the local agency"s board president, the El Paso Times reports. According to the agency, 56 percent of the center"s budget was earmarked for HIV/AIDS programs, while 30 percent was for family planning and primary health care. Lynn Salas, board president of the El Paso Planned Parenthood, said, "The [Planned Parenthood Federation of America] felt our AIDS/HIV programs had grown so much we were not focusing enough on the core mission, and we began in mid-March to plan the changes we are still working out" (Valdez, El Paso Times, 6/3).
Following President Obama"s nomination of Judge Sonia Sotomayor to replace retiring Supreme Court Justice David Souter, the differences between how male and female judges see and rule on cases has come into question, the New York Times reports. Although retired Supreme Court Justice Sandra Day O"Connor, the first woman to serve on the Supreme Court, often said that a female judge would come to the same decision as a male judge, Justice Ruth Bader Ginsburg has said that her perspective on certain cases is different because of her gender.The Times cites two examples, one involving the strip search of a 13-year-old girl -- to which Ginsburg said that her male colleagues could not understand how the girl felt. The second example involves the issue of certain abortion procedures. When deciding about the constitutionality of a federal ban on so-called "partial-birth" abortions, Ginsburg took issue with Justice Anthony Kennedy"s majority opinion that women who undergo the procedure likely would experience attacks of conscience. She responded that Kennedy"s views reflected "ancient notions of women"s place in the family and under the Constitution -- ideas that have long since been discredited."The issue has come up again with Sotomayor"s nomination, specifically regarding her 2001 statement that she "would hope that a wise Latina woman with the richness of her experiences would more often than not reach a better conclusion than a white male who hasn"t lived that life." The perception that female judges inherently might view cases differently than male judges has raised some concerns even among some female judges who believe it might be true, according to the Times. Judge Judith Kaye, former chief judge of New York state, said that she avoided discussing the issue with others but then accepted the idea that female judges see things differently at times. "To defend the idea that women come out different on some cases, I just feel it," Kaye said, adding, "I feel it to the depths of my soul" because women"s experiences are "just different." Attorney Lawrence Robbins, however, said, "Any person in the real world should be highly reluctant to make these broad generalizations."The most recent study comparing male and female judges found that female judges were more likely to rule in favor of plaintiffs who claim sex discrimination at workplaces. The study also found no differences in cases involving disability law, environmental issues and capital punishment (Lewis, New York Times, 6/3).
It takes less than a minute for a stroke to change a person"s life forever, but taking the time to make a few simple lifestyle adjustments and finding out how to recognize an attack when it happens can save thousands of lives.
Everyone checks their body to some extent, but many people with eating disorders repeatedly check their body and often in a way that"s unusual.
Pandinus imperator, the emperor scorpion, is not only popular as a pet, but is also of interest for research purposes. The reason for this is its blue blood, which transports oxygen and distributes it throughout the body. Like tyrosinase, the key enzyme in melanin synthesis, the blue blood pigment hemocyanin found in the emperor scorpion and other arthropods belongs to a group of special molecules that occur in all organisms and that have many different functions: coloring the skin, hair and eyes, immune response, wound healing or the brown discoloration of fruit. "When these enzymes mutate, this may result in albinism, or in birth marks when production of the pigment melanin increases, as often seen in melanoma," explains Professor Heinz Decker of Johannes Gutenberg University Mainz. The biophysicist has been studying hemocyanins and the associated tyrosinases for the past 20 years. In cooperation with researchers, Dr. Cong and Dr. Chiu, from the Baylor College of Medicine in Houston he has now been able to show for the first time exactly how the enzymes become active, thereby fulfilling their various functions. This work was published in the journal Structure on 13 May.
The results of the RECORD study are reported in an article published Online First and in a future edition of The Lancet. The findings are presented at the same time at the American Diabetes Association (ADA) meeting in New Orleans, USA. They indicate that the use of rosiglitazone (Avandia) together with regular diabetes treatments (metformin or a sulfonylurea) to reduce blood glucose in type 2 diabetics does not raise the risk of cardiovascular disease or death. On the other hand, the research establishes that using rosiglitazone multiplies by more than two the risk of heart failure, and increases the risk of fracture, mostly in women.
The first of six online courses to educate healthcare professionals on preventing the transmission of healthcare-associated infections (HAIs) is being launched by the Association for Professionals in Infection Control and Epidemiology (APIC). Healthcare-associated infections (HAIs) cause 99,000 deaths in the U.S. each year.
Many children who are retained in kindergarten, first or third grade for academic reasons do not subsequently receive a document outlining the individualized special education services they should receive, according to a report in the June issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
Adding AZD3355, a novel GABAB receptor agonist, to a proton pump inhibitor (PPI) in patients with Gastroesophageal Reflux Disease (GERD), resulted in a 35% reduction in the mean total number of reflux episodes 0-24 hours after dose, compared with placebo.[i] These data were presented at the Digestive Diseases Week annual meeting (DDW®, 30 May - 4 June, Chicago).
Improvements in diagnosis and treatment over the past 30 years have led to a 17% decrease in the likelihood of death from aneurysmal subarachnoid haemorrhage (the bursting of a blood vessel on the surface the brain) in the general population, according to an Article published Online First and in the July edition of The Lancet Neurology.
One in every 3,000 babies is born with an inborn error of metabolism -- a genetic defect that interferes with their ability to process substances like carbohydrates, proteins and fats. Until recently, tests to detect many of these very rare, disabling, and sometimes fatal disorders like fatty acid oxidation disorders were rarely used. If the child died, the cause would be listed as unknown or Sudden Infant Death Syndrome (SIDS). If they survived, they would experience a range of symptoms and medical problems throughout their lives such as delays in development, seizures, difficulty with growth and autistic behavior.
SRI International, an independent, nonprofit research and development organization, has announced that that it will screen a library of well-characterized drugs against the 2009 H1N1 influenza A virus, previously known as "swine flu." The work will be performed under a re contract from the Division of Microbiology and Infectious Diseases (DMID) in the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
"With a continuously ageing population the incidence of osteoporosis is steadily rising. This does not only pose problems to the individuals concerned but is also an enormous challenge for our societies" according to Professor Wolfhart Puhl, past president of the European Federation of National Associations of Orthopaedics and Traumatology (EFORT). Prof. Puhl, of the Orthopç¤dikum Allgç¤u, Germany, who is in Vienna for the EFORT Congress, emphasized that the problem"s "dimension is frequently underestimated. Policy makers and funding agencies do not always consider this development sufficiently in their planning."
Increasing population density, rather than boosts in human brain power, appears to have catalysed the emergence of modern human behaviour, according to a new study by UCL (University College London) scientists published in the journal Science. High population density leads to greater exchange of ideas and skills and prevents the loss of new innovations. It is this skill maintenance, combined with a greater probability of useful innovations, that led to modern human behaviour appearing at different times in different parts of the world.
Cervical Cancer Awareness Week 8-14 June 2009 is a key time to remind women that it is of huge importance that they attend their screening appointment when asked. The Improvement Foundation (IF) aim to help tackle the decline in screening uptake by addressing levels of complacency among clinicians and the public through their national Cervical Screening Improvement Programme.
An Australian psychiatrist believes Britain"s stiff upper lip culture, class system and the NHS means we are not supporting the mental health needs of war veterans adequately.
The focus on acute stroke in the UK government"s national stroke strategy may distract attention and res from other important elements of stroke care, warn experts in a paper published on bmj.com today.
Versartis, Inc., a new company developing novel biologics with enhanced properties for patients with metabolic diseases, published abstracts for preclinical data on its two product candidates, VRS-859 (exenatide-rPEG) and VRS-808 (glucagon-rPEG), at the American Diabetes Association Scientific Sessions annual meeting beginning today in New Orleans.
ActoGeniX, a development stage biopharmaceutical company, announced that the United States÷´ Food and Drug Administration (FDA) has approved the Company÷´s Investigational New Drug (IND) application for AG013, a novel therapeutic product for the treatment of oral mucositis in cancer patients. This IND application approval allows ActoGeniX to initiate a phase 1B clinical trial with AG013, which will now become the second clinical development program in ActoGeniX÷´s portfolio.
In recent decades, there have been periodic reports of a worldwide decline in sperm count and quality. Male infertility has ostensibly been on the rise, accompanied by increases in testicular cancer and hypospadias -- a congenital defect in which the opening of the urethra is on the underside, rather than at the end, of the penis. Taken together, these three conditions have been termed testicular dysgenesis syndrome.
Both blood pressure and serum lipid levels have improved in Swedish middle-aged women during the past 30 years. Levels of perceived mental stress, however, have increased significantly. These are the of a thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden.
President Obama has named Alexia Kelley -- Catholics in Alliance for the Common Good co-founder and former executive director -- to the position of director of Faith-Based and Community Partnerships at HHS, Salon"s "War Room" reports. According to Salon"s the "War Room," CACG primarily has worked to find ways to reduce the demand for abortion procedures rather than advocate for laws to restrict access. However, CACG"s Web site reads, "Catholics in Alliance believes in the sanctity of all human life -- from conception until natural death" (Madden, "War Room," Salon, 6/4).Catholics for Choice President Jon O"Brien writes in The Hill"s "Congress Blog" that the appointment is "a defeat for reason and logic" and "calls into question whether President Obama"s administration is serious about reducing the need for abortion." According to O"Brien, Kelley "is on record with her support for restrictions on access to abortion," although CACG has sought to "avoid the question of legalization at every turn." O"Brien continues that the group also used "flawed economic data to support anti-poverty measures as a means to reduce the number of abortions," and "opposed evidence-based prevention methods such as contraception and comprehensive sexuality education" (O"Brien, "Congress Blog," The Hill, 6/4).Officials at the White House and HHS did not return calls for comment. CACG spokesperson Jennifer Goff said, "Catholics in Alliance for the Common Good is working toward reaching common ground in order to make real progress on the moral and political challenges our country faces instead of resorting to spurious attacks launched by those who are more concerned with inflaming the culture wars than effecting positive change" ("War Room," Salon, 6/4).
The recent murder of Kansas abortion provider George Tiller has prompted other providers nationwide to reassess their need for protective measures against violent actions from opponents of abortion rights, the AP/San Francisco Chronicle reports. In the days following Tiller"s murder, many clinic officials nationwide said that they had contacted law enforcement and examined their existing security measures. U.S. Attorney General Eric Holder also ordered the U.S. Marshals Service to provide security to several clinicians and facilities. According to the AP/Chronicle, violence against abortion providers in the 1980s and 1990s forced many to take various precautionary measures in and around their clinics, while some underwent training to protect themselves.Kate Michelman, former president of NARAL Pro-Choice America, said the election of former President George W. Bush, an abortion-rights opponent, helped alleviate some violence against abortion providers. However, she said that she believes Tiller"s murder might indicate the situation is changing during the first months of President Obama"s administration. Obama has rejected abortion-rights opponents" calls for restrictions on the procedure and also reversed the "global gag rule," or "Mexico City" policy.Michelman said, "Historically, when those who oppose a woman"s right to decide are frustrated politically, they get more violent," adding, "I have been thinking about this ever since the [Obama] election." She said that some providers will remain fearful even though she believes clinics are now safe. "In the end ... if someone is out to get you and they are determined and have a chorus encouraging them, ... there"s not much you can do to stop them," Michelman said. Provider LeRoy Carhart, who provided abortion services at Tiller"s clinic, said that people who commit violence against abortion providers should be charged with hate crimes (Hanna, AP/San Francisco Chronicle, 6/3).
Sen. Max Baucus, D-Mont., chairman of the Finance Committee expects the Senate"s health care overhaul proposal to include a public health insurance plan, Dow Jones Newswire reports, adding that Baucus was "following the lead of President Obama and drawing a line in the sand on the controversial issue." The President strongly supported the public option in a letter to senators Wednesday.
The Office of the National Coordinator for Health Information Technology"s number-two man, Charles Friedman, told industry members that an official definition of the term "meaningful use" of health information technology is "in the works" and they should expect its release "in the not too distant future." "Meaningful use" refers to the criteria the government will use to determine whether to pay providers for adopting the technology, Modern Healthcare reports.
As state revenues continue their downturn due to the recession, 16 states are trying to find ways to deal with increased health care costs, The New York Times reports: "The carnage in state budgets is getting worse, a report said Thursday, with places like Arizona being hurt by falling revenue on multiple fronts, like personal income and sales taxes. Other states are having mixed experiences, with some tax categories stable, or even rising, even as others fall off the map."
Given Imaging Ltd. (NASDAQ: GIVN) announced a new study that shows over half of the eligible patients with occult or obscure gastrointestinal bleeding (OGIB) may benefit from the additional diagnostic information provided by small bowel capsule endoscopy in accordance with existing gastrointestinal (GI) society guidelines, which call for the patient-friendly, non-invasive procedure following a negative upper endoscopy and colonoscopy. Additional studies advocate broader utility of capsule endoscopy in iron deficiency anemia (IDA) and suspected small bowel Crohn"s disease. The studies were presented at the Digestive Disease Week(R) (DDW) 2009 conference taking place in Chicago from May 30 - June 4, where Given Imaging also demonstrated a new, simplified procedure for performing PillCam(R) capsule endoscopy of the small bowel and the latest version of its RAPID(R) Software Suite at booth #2235 at the conference.
Musculoskeletal problems are among the complaints most frequently reported in health interview surveys. Typically around 50 percent of the population report having had musculoskeletal pain in one or more areas for at least one week during the past month. Musculoskeletal disorders are also the most common work-related health problems in the EU: 25 percent of European workers complain of backache and 23 percent of muscular pains. The trend will become even more acute as demographic changes lead to an ageing society.
DaVinci Biosciences LLC in collaboration with University of Utah, Southern California Center for Regenerative Medicine and Omni Hospital in Ecuador, announce the discovery of a previously unidentified stem cell population from adult human testis in Biochemical and Biophysical Research Communications (BBRC), an international peer-reviewed journal focused on the rapid dissemination of timely and significant experimental results in diverse fields of biological research. Termed gonadal stem cells (GSCs) these adult derived stem cells, unlike previous reported population of stem cells found within the testis, have been found to demonstrate adult stem cell properties. Published in the current journal of Biochemical and Biophysical Research Communications, the data from this collaborative study describes a multipotent adult stem cell population that has the capacity to readily differentiate into multiple cell types. The study evolved from an international collaboration aimed at identifying novel cell populations at different geographical laboratory locations and for different HLA types.
The NMC has started work to improve its advice and information on whistle-blowing for nurses and midwives.
Merck & Co., Inc. said that preliminary results for the pivotal Phase III study of rolofylline (MK-7418), the Company"s investigational medicine for the treatment of acute heart failure, show that rolofylline did not meet the primary or secondary efficacy endpoints. While Merck will continue to analyze the data with outside experts, the Company will not file applications for regulatory approval this year. The results from this study will be presented at a medical meeting later this year.
The decriminalisation of dispensing errors is an issue that has united the profession.
Dietitians of Canada and Kraft Canada have announced the winners of the 12th annual Speaking of Food and Healthy Living Award - an annual competition designed to showcase and encourage collaborative efforts that help Canadians make informed choices about healthy eating and physical activity.
The Hawai"i Tumor Registry (HTR), jointly operated by the Cancer
HCL, the UK"s largest specialist health and social care recruiter, said that the rising proportion of women doctors will lead to a greater emphasis on flexible working and the use of locums in the medical workforce.
Medtronic, Inc. (NYSE: MDT) announced results of a randomized, controlled trial to demonstrate the benefits of an insulin pump therapy augmented with real-time continuous glucose monitoring (Personal CGM) versus a conventional pump and self-monitoring of blood glucose in type 1 diabetes patients with poor metabolic control. Study findings showed that patients who used Personal CGM more than 70 percent of the time achieved nearly a full percentage point reduction in A1C (average blood glucose levels). The results were presented at the 69th Annual Scientific Sessions of the American Diabetes Association (ADA) in New Orleans.
Cancer Research Technology (CRT) and The Institute of Cancer Research (ICR) announced a major research collaboration with AstraZeneca. The three partners will combine their expertise to discover and develop potential new anti-cancer drugs to target molecular "chaperones" which support the growth of cancer cells.
Diamyd Medical reported that the company has received approval from the US Food and Drug Administration (FDA) to include children with type 1 diabetes from 10 years of age in the company"s Phase III study with the diabetes vaccine Diamyd(R).
Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN) and Eli Lilly and Company (NYSE: LLY) announced interim results from a retrospective study including nearly 260,000 patients that showed the risk of acute pancreatitis among patients initiating therapy with BYETTA(R) (exenatide) injection was not increased compared to patients initiating other antidiabetic therapies. These findings were presented at the 69th Annual Scientific Sessions of the American Diabetes Association (ADA) in New Orleans.
Mental health care must improve to halt the staggering number of suicides occurring in prisons, new research has revealed.
Congressional Democrats are preparing the message to go with their sweeping health reform in both the House and the Senate, after Sen. Edward Kennedy"s draft reform bill was circulated, CNN.com reports.
Consumer concern over the swine influenza outbreak has reinforced the
A new study finds that many women with breast cancer take antioxidant supplements while undergoing cancer treatment, even though the consequences of doing so are unknown. Published in the July 15, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study indicates that additional research should be undertaken to determine the effects of antioxidant supplementation on the health and survival of breast cancer patients.
According to a research abstrac presented on June 8 at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, days with increased activity were followed by nights with lower total sleep time (TST), while nights with lower TST were followed by increased activities during the next day.
According to a research abstract presented on June 8 at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, in the presence of free access to food, sleep restricted subjects reported decrease in appetite, food cravings and food consumption; however, they gained weight over the course of the study. Thus, the finding suggests that energy intake exceeded energy expenditure during the sleep restriction
Primary care pediatricians may be under-diagnosing sleep disorders in children and teens, according to a research abstract presented on June 8 at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies.
Napping may have a significant influence on young children"s daytime functioning, according to a research abstract presented on Monday, June 8 at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies.
In recognition of World Blood Donor Day on June 14th, the National Anemia Action Council (NAAC) is providing the online tutorial Anemia & Blood Donation to blood donors who have been deferred because of a low blood count.
According to a research abstract presented on June 8, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, active problem solving strategies are associated with successful use of continuous positive airway pressure (CPAP) therapy for the treatment of obstructive sleep apnea (OSA).
Being overweight is a health concern, and using only body mass index (BMI) to determine weight classification may not give an accurate picture of a person"s health, according to an advisory published in Circulation: Journal of the American Heart Association.
Although alcohol consumption is known to be associated with chronic pancreatitis, new evidence indicates that a threshold of five or more drinks per day is required to significantly raise risk; however, most patients with chronic pancreatitis do not drink this amount, according to a report in the June 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. In addition, smoking is an independent, dose-dependent risk factor.
Coronary heart disease (CHD) is the leading cause of death worldwide and a major driver of medical and economic costs, especially among older adults. It has long been established that cardiac rehabilitation improves survival, at least in middle-aged, low- and moderate-risk white men. Now a large Brandeis University-led study published in the Journal of the American College of Cardiology reports that older cardiac patients benefit as much from cardiac rehab as their younger counterparts.
Vaccines intended to help the body to fight off the flu bug may actually give the bug an edge, researchers say.
As Memorial Day Weekend and the opening of the summer beach season fast approach, The Cancer Institute of New Jersey (CINJ) is making experts available to discuss the risks of developing skin cancer and what steps can be taken to prevent it.
This Sunday, thousands of people around the globe will join the
With MPs due to debate the Health Bill in the House of Commons, the BMA is urging them to support measures that will help prevent young people from taking up smoking.
This statement updates Members on the swine flu outbreak and the latest developments in Wales and across the UK.
A CT scan stands for Computed Tomography scan. It is also known as a CAT (Computer Axial Tomography) scan. It is a medical imaging method that employs tomography. Tomography is the process of generating a two-dimensional image of a slice or section through a 3-dimensional object (a tomogram). The medical device (the machine) is called a CTG scanner; it is a large machine and uses X-rays. It used to be called an EMI scan, because it was developed by the company EMI. Undergoing a CT scan is a painless procedure.
The results from the phase II SYNCHRONY study are published in an article Online First and in a future edition of The Lancet. At the same time, the findings are presented at the American Diabetes Association meeting in New Orleans, USA. They suggest that aleglitazar, a treatment for type 2 diabetes, might be safe and effective and may perhaps be introduced into phase III trials.
BioMarin Pharmaceutical Inc. (Nasdaq: BMRN) announced results from the Phase 1 clinical study of PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase) for the treatment of phenylketonuria (PKU). The company expects to initiate the Phase 2 clinical study in late June or early July, pending institutional review board (IRB) approval from the clinical trial sites. The U.S. Food and Drug Administration (FDA) has reviewed the Phase II clinical trial protocol.
United Therapeutics Corporation (Nasdaq: UTHR) and Eli Lilly and Company (NYSE: LLY) today announced the results of a pivotal 16-week study showing that a once-daily dose of tadalafil was generally well tolerated, improved exercise capacity and improved time to clinical worsening in patients with pulmonary arterial hypertension (PAH)(1). The randomized, double-blind, 16-week, placebo-controlled Phase 3 study followed 405 patients with PAH, either treatment-naive or taking bosentan, randomized to placebo or tadalafil 2.5 mg, 10 mg, 20 mg or 40 mg orally. Results from the study entitled, "Tadalafil Therapy for Pulmonary Arterial Hypertension," were published in today"s issue of Circulation.
A veterinarian at Kansas State University"s College of Veterinary Medicine has advice for pet owners who want to consider how pets fit into their own household emergency plans -- especially if that includes evacuating.
A small study published in Acupuncture Medicine reports that acupuncture may be beneficial in easing symptoms of indigestion which are very frequent in pregnant women. The hormonal changes in the body during pregnancy cause heartburn, stomach pain and discomfort, reflux, belching and bloating. Between 45 to 80 percent of women are reported to experience those symptoms.
The WHO and UNICEF on Tuesday said that vitamin A supplements and deworming tablets are safe, after two deaths and the "sickness of hundreds" were alleged among the children who received the interventions during a nationwide campaign in Bangladesh, Bernama.com reports (Bernama.com, 6/9).
Despite a recent ruling by India"s Supreme Court that all tobacco products must have pictorial warnings by May 31, one week after the ruling was to go into effect, the warning labels have yet to appear on packaging, the National reports.
"The new swine influenza virus [H1N1], which appeared suddenly after years of warning about a potential pandemic of avian influenza, upset the WHO"s assumptions that most people have the same understanding of the word pandemic," says the New York Times in a report that examines the difficultly health experts have had when attempting to agree upon what constitutes a pandemic.
Access To Second-Line Antiretrovirals In India
A California Restaurant Association has asked the Supreme Court to rule on the legality of San Francisco"s mandate that employers pay for health care coverage for employees, The San Francisco Chronicle reports.
President Obama"s appointment of Alexia Kelley, founder of Catholics in Alliance for the Common Good, as director of the Office of Faith-Based and Community Partnerships at HHS "took the pro-choice movement by surprise," Salon contributor Frances Kissling, a former president of Catholics for Choice, writes in an opinion piece. According to Kissling, abortion-rights supporters "want to know ... why the post, which includes oversight of the department"s faith-based grant-making in family planning, HIV and AIDS and in small-scale research into the effect of religion and spirituality on early sexual behavior, has gone to someone who both believes abortion should be illegal and opposes contraception." She adds that Kelley and CACG have "sought to narrow the interpretation of common ground on abortion to efforts to reduce the number of abortions by providing women who are already pregnant with economic support for continuing the pregnancy and making adoption easier."Kissling notes that the "HHS budget for family-planning services grants to faith-based and community groups is more than $20 million." She asks, "Can pro-family-planning religious groups expect a fair deal from a director who believes that birth control, even for married couples, is immoral? Will programs that provide contraception to adolescents get funded?" Kissling continues that Obama"s February executive order on the office directed it to work to prevent teen pregnancy and reduce the need for abortion. She says of Kelley, "How can an opponent of the single most effective way to do both -- contraception -- lead that effort in HHS enthusiastically and effectively?"Kissling also notes Kelley"s accomplishments, writing that she "has much to offer in government -- but not at HHS." There are "10 other government agencies that have faith-based offices," and a "far less controversial placement could have been found at Labor, Housing and Urban Development, or the Department of Education," according to Kissling.Kissling continues that some leaders in the abortion-rights movement "have not yet commented on the Kelley appointment; most are still reeling from Dr. Tiller"s murder." However, "One hopes they will turn their attention to this appointment and demand a review of Kelley"s qualifications for this post," Kissling writes. She continues, "Pro-choice groups also contributed to the president"s election. They deserve appointees who agree with the platform on which the president ran. The pro-choice movement"s recommendations for pro-choice appointees to the faith-based office"s advisory council were ignored."Kissling adds that the "mission going forward must be to ensure that any additional staff members appointed to faith-based centers in Cabinet-level agencies reflect the pro-choice, pro-family-planning values of the administration." She concludes that as abortion-rights supporters "try to get to the bottom of the Kelley appointment, greater oversight of, and consultation on, future appointments need to be secured" (Kissling, Salon, 6/7).
Employees who often go to work despite feeling sick have higher rates of future work absences due to illness, according to a study in the June Journal of Occupational and Environmental Medicine, official publication of the American College of Occupational and Environmental Medicine (ACOEM).
According to a research abstract that will be presented on Wednesday, June 10, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, getting more high-quality sleep is associated with better academic performance. The positive relationship is especially relevant to performance in math.
Appeals Court Judge Sonia Sotomayor -- whose is considered to be "near the top" of President Obama"s list of potential Supreme Court nominees to replace retiring Justice David Souter -- could face criticism over a 2001 speech in which she stated that a judge"s ethnicity and gender "may and will make a difference in our judging," the New York Times reports. According to the Times, Republicans have indicated that "they intend to put the eventual nominee under a microscope," and they have expressed concern that Obama"s emphasis on judicial "empathy" suggests that he is seeking a judge who will promote liberal ideology. Some conservative commentators also have branded Sotomayor a "judicial activist" because of her remarks during a 2005 panel discussion for law students, when she said that a "court of appeals is where policy is made." However, Sotomayor also said that she is "not promoting" and "not advocating" that idea.In her 2001 speech, delivered at the Judge Mario G. Olmos Law and Cultural Diversity Lecture at the University of California-Berkeley, Sotomayor questioned the notion that male and female judges would reach similar conclusions when deciding cases, though she also "sounded many cautionary notes," the Times reports. Sotomayor said, "I would hope that a wise Latina woman with the richness of her experiences would more often than not reach a better conclusion than a white male who hasn"t lived that life." Sotomayor also said that the increasing diversity in federal courts "will have an effect on the development of the law and on judging." She said that being a woman or a minority can affect a judge"s perspective because of "experience or inherent physiological or cultural differences."However, Sotomayor also said that women and minority groups do not all share a universal perspective and that she was not referring to any specific case. Although she said that she strives to question her own "opinions, sympathies and prejudices," and aspired to impartiality, she also asked whether achieving impartiality is "possible in all, or even in most, cases." Sotomayor said, "I wonder whether by ignoring our differences as women or men of color we do a disservice to both the law and society?" She added, "Personal experiences affect the facts that judges choose to see." Charles Ogletree, a Harvard Law School professor and adviser to Obama, said Sotomayor"s remarks were appropriate because it is "obvious that people"s life experiences will inform their judgments in life as lawyers and judges" (Savage, New York Times, 5/15).
A leading anxiety charity has today criticised Veteran Labour MP Sir Gerald Kaufman for using Obsessive-Compulsive Disorder as an excuse for, by his own admittance "bizarre and daft" MP expense claims.
Antibiotics, antimicrobials and antifungals are seeping into the waterways of North America, Europe and East Asia, according to an investigation published in the peer-reviewed journal Environmental Health Perspectives (EHP). Authored by Université de Montréal and Environment Canada researchers, the review found that consumption of anti-infectives for human and agriculture use contributes to their release into the environment and even into drinking water.
Residential childcare and fostering agency, Perpetual Care, and the University of Central Lancashire"s School of Nursing & Caring Sciences are jointly developing an introductory workshop on the ground-breaking Nurtured Heart Approach, which seeks to improve social and educational outcomes for many children and young people. Experts from UCLan and Perpetual are currently designing an awareness workshop, which will provide an overview of the approach, examine existing US research findings and explore its potential role in UK residential childcare and fostering, particularly in the light of revised NICE guidelines relating to children with ADHD. The first session is scheduled at UCLan"s Preston campus in late June this year and should be of interest to registered social workers, local authority placement officers and other social care and health professionals concerned with the well-being of challenging young people.
A research abstract presented on June 9, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, is the first demonstration of a specific neurochemical abnormality in adults with primary insomnia (PI), providing greater insight to the limited understanding of the condition"s pathology.
Individuals with insomnia and objective short sleep duration are at increased risk for developing diabetes, according to a research abstract presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies.
Considerable discrepancies have been reported between diagnoses of colorectal epithelial neoplastic lesions made by Western and Japanese pathologists from endoscopic cold biopsies and resected specimens of the same lesions
When we talk about exercise, we nearly always refer to physical exercise. Exercise is the physical exertion of the body - making the body do a physical activity which results in a healthy or healthier level of physical fitness and both physical and mental health. In other words, exercise aims to maintain or enhance our physical fitness and general health. People exercise for many different reasons. Some of them are included below:
Restaurants in Germany legally sell alcohol to teenagers after their sixteenth birthdays and French children drink wine with dinner at an early age, but U.S. parents who follow this relaxed European example, believing it fosters a healthier attitude toward alcohol, should be careful -- it may increase the likelihood that their children binge drink in college.
New research from Jefferson Hospital for Neuroscience (JHN) may redefine how Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is diagnosed. Eduardo De Sousa, M.D., assistant professor of Neurology at Jefferson Medical College of Thomas Jefferson University, and director of the Electrodiagnostic Neuromuscular Lab at JHN, led the study which looked at the number of demyelinating features that are needed to differentiate between CIDP, Amyotrophic lateral sclerosis (ALS, or Lou Gehrig"s disease) and diabetic neuropathy. His research suggests a minimum number of three demyelinating features can be used to positively identify CIDP in a patient. CIDP is a neurological disorder characterized by progressive weakness and impaired sensory function in the legs and arms. It affects about 50,000 people in the United States. The study, available in the current edition of the Journal of Clinical Neuromuscular Disease, may help doctors more effectively diagnose and treat CIDP.
Exposure during pregnancy to the chemical bisphenol A, or BPA, found in many common plastic household items, is known to cause a fertility defect in the mother"s offspring in animal studies, and now researchers have found how the defect occurs. The results of the new study will be presented Saturday at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
Hormonal changes early in pregnancy cause maternal postpartum anxiety and behavior changes that can lead to a delayed onset of puberty in both birth and adoptive daughters, according to a new study conducted in mice. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
New post-hoc analyses, presented at the American Diabetes Association (ADA) 69th Annual Scientific Sessions, of data pooled from studies of 104 weeks in duration showed "Januvia" (sitagliptin), when taken alone* (2 studies) or in combination with metformin (2 studies), provided significant blood sugar lowering, which was sustained over two years.[i]
Researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal"s Jewish General Hospital - along with colleagues at the University of Manitoba and the University of British Columbia - may have found a chink in the armour of the human immunodeficiency virus type 1 (HIV-1), the microorganism which causes AIDS. They have pinpointed the key cellular machinery co-opted by HIV-1 to hijack the human cell for its own benefit. Their study was published in May in the Journal of Biological Chemistry.
Over 100,000 people suffer from multiple sclerosis in Germany alone. Despite intensive research, the factors that trigger the disease and influence its progress remain unclear. Scientists from the Max Planck Institute of Neurobiology in Martinsried and an international research team have succeeded in attaining three important new insights into the disease. It would appear that B cells play an unexpected role in the spontaneous development of multiple sclerosis and that particularly aggressive T cells are activated by different proteins. Furthermore, a new animal model is helping the scientists to understand the emergence of the most common form of the disease in Germany. (Nature Medicine, May 31, 2009 & Journal of Experimental Medicine, June 1, 2009)
Versartis, Inc., an emerging company developing novel biologics with enhanced properties for patients with metabolic diseases, presented data for its long-acting product candidates, VRS-317 (hGH-rPEG) for treatment of growth hormone deficiency and for VRS-826 (IL-1ra-rPEG) for treatment of type 1 and type 2 diabetes, at the Endocrine Society"s Annual Meeting in Washington, DC.
InteKrin Therapeutics Inc presented Phase 2a clinical study results at the American Diabetes Association annual meeting in New Orleans demonstrating that once a day oral treatment with INT131 provides anti-diabetic efficacy consistent with maximal dose thiazolidinedione (TZD) therapy but with less hematocrit reduction and weight gain.
The American Academy of Pediatric Dentistry (AAPD), the recognized leader in pediatric oral health, announced new oral health guidelines for expectant mothers and infants following its 62nd Annual Session in Honolulu, Hawaii. The guidelines call for all pregnant women to receive counseling and oral healthcare during pregnancy, and also that infants receive an oral health risk assessment and oral care by their first birthday. These steps will contribute to optimal oral health for both mom and baby.
The Desert Sun published a series of articles related to HIV/AIDS. The articles include a feature profiling people living with the virus and others looking at efforts by advocates to offer culturally appropriate information on HIV to Hispanics, blacks and other minorities; the efficacy of antiretrovirals, and how the drugs are enabling people to live longer; and the potential effects of proposed state budget cuts on HIV/AIDS programs in Riverside County (Brambila, Desert Sun, 6/10).
Strativa Pharmaceuticals, the proprietary products division of a wholly owned subsidiary of Par Pharmaceutical Companies, Inc. (NYSE: PRX), today announced that the U.S. Food and Drug Administration (FDA) has accepted its New Drug Application (NDA) for ondansetron orally dissolving film strip (ODFS). Strativa is seeking approval of ondansetron ODFS for the prevention of nausea and vomiting associated with highly- and moderately-emetogenic chemotherapy, radiotherapy and surgery.
Drug maker GlaxoSmithKline (GSK) on Tuesday opened a $600 million plant in Singapore that is slated to begin producing vaccines to fight pneumonia-causing bacteria in 2011, Reuters reports.
Democratic leaders have begun moving the rank and file closer to acceptance of basic tenets of health reform proposals, but concerns remain among the fiscally conservative Blue Dog Democrats on how it will be paid for, Politico reports.
Seventy-three percent of insured patients receiving assistance from Patient Access Network (PAN) Foundation reported that health care costs are influencing their medication and treatment decisions more this year than last. Nearly half of these said that cost is having a "very big" or "big" impact on whether they seek treatment or fill prescriptions.
Nearly two-thirds (63 percent) of African Americans with high blood pressure (also known as hypertension) say they worry more about their finances than their personal health, according to a new "My Pressure Points"(TM) national survey commissioned by Daiichi Sankyo, Inc., in collaboration with the Association of Black Cardiologists.(1) In addition, almost half (48 percent) are stressed about their work and careers. Everyone juggles many external pressures in everyday life like jobs, finances and family care. But while those African Americans surveyed have increased their focus on the external pressures, have they lost sight of a critical internal pressure - one that can impact every facet of their lives? The survey was designed to test this hypothesis.
Researchers at UMDNJ-Robert Wood Johnson Medical School are a step closer to treating, and perhaps preventing, muscle damage caused by disease and aging. In their study, published in the June issue of Journal of Biological Chemistry, the scientists have linked the newly discovered protein MG53 to a pathway that repairs human muscle tissue along with the proteins caveolin-3 (Cav3) and dysferlin. Prior to this study, the underlying interactions that inhibited membrane repair in muscle tissue were unknown. Linking these proteins creates a mechanism that allows damaged membranes to be repaired, which may transform treatment for patients who suffer from severe complications of diseases such as muscular dystrophy, as well as cardiovascular disorders and conditions related to advancing age.
The family of murdered Kansas abortion provider George Tiller announced on Tuesday that his Wichita clinic will not re-open, leading some abortion-rights advocates to voice concern about access to the procedure, the New York Times reports. Tiller was one of a handful of abortion providers who performed the procedure in the second and third trimesters of pregnancy, and women for decades have traveled to the clinic from across the U.S. and other countries. The clinic, Women"s Health Care Services, also was Kansas" only clinic outside the Kansas City area (Davey, New York Times, 6/10). The Tiller family said in a statement that the clinic will be "permanently closed" effective immediately. The family also said it does not plan to be involved "in any similar clinic" but will "honor Dr. Tiller"s memory through private charitable activities" (Slevin/Stein, Washington Post, 6/10).While abortion-rights advocates expressed empathy for the family, some added that they also are concerned that the clinic"s closure could have devastating effects for women who learn of fatal health problems late in their pregnancies, the Times reports. Nancy Northup, president of the Center for Reproductive Rights, said, "It is unacceptable that antiabortion intimidation and violence has led to the closing of Dr. Tiller"s clinic." She added, "Not only have we lost a fearless defender of women"s fundamental health and rights in Dr. Tiller"s murder, but the closing of his clinic leaves an immediate and immense void in the availability of abortion" (New York Times, 6/10). Suzanne Poppema, board chair of Physicians for Reproductive Choice and Health and a retired ob-gyn who performed abortions, said that abortions later in pregnancy would still be available, including through university hospitals that do not advertise the service. The closing is "not going to stop people who want to provide the service, but it will slow them down," she said. Marla Patrick, Kansas coordinator for the National Organization for Women, said abortion-rights advocates are working to open another Wichita-based clinic that provides abortions later in pregnancy (Bello, USA Today, 6/10). The AP/Yahoo! News reports that Kansas state law permits abortion after 21 weeks" gestation only if continuing the pregnancy would endanger the woman"s life or cause a "substantial and irreversible impairment" of a major bodily function, which courts have interpreted to include the mental health of the woman (Hegman/Hanna, AP/Yahoo! News, 6/9).According to the Times, some abortion-rights advocates had hoped other abortion providers would take over Tiller"s work at the clinic. LeRoy Carhart, a Nebraska abortion provider who also worked with Tiller, said he is "currently exploring every option to be able to continue to make second- and early, medically indicated third-trimester abortions available." Warren Hern, a Colorado abortion provider who performs procedures later in pregnancy, said, "Where does it end? The antiabortion fanatics got exactly what they wanted" (New York Times, 6/10). According to the Wall Street Journal, abortion-rights opponents" response to the closure was "subdued." Some expressed concern that antiabortion-rights extremists would think that violence "gets results where legal protest doesn"t," the Journal reports (Simon, Wall Street Journal, 6/10). Troy Newman, president of Operation Rescue, said that while the group is "thankful" that the clinic is closed, they "wish it would have come through the peaceful, legal channels that we were pushing" (New York Times, 6/10).Broadcast CoverageMSNBC"s "The Rachel Maddow Show" on Tuesday reported on the clinic"s closure and included a discussion with Susan Hill, president of the National Women"s Health Organization, about violence against abortion providers and an increase in the hostility of protesters outside abortion clinics since Tiller"s murder (Maddow, "The Rachel Maddow Show," MSNBC, 6/9). NPR"s "All Things Considered" on Tuesday also reported on the clinic"s closure ("All Things
Physician representatives will gather in Copenhagen in September to discuss the health consequences of climate change to ensure that the medical profession"s voice is heard when a new global climate treaty to replace the Kyoto accord is considered two months later.
"Blog Watch" offers readers a roundup of health policy-related blog posts.Appropriately, the last of the Senate Finance Committee"s three major public roundtables on health reform issues was on finance. Keith Hennessy lauds economist Kate Baicker"s testimony (.pdf) and says it helps connect reform ideas to a system of third-party payment. Hennessy says the current system leads people to "spend more of other people"s money than they do of their own, and less wisely." Hennessy explores the example of employer-sponsored insurance, which he says makes health insurance appear less expensive to employees than it is.Meanwhile, the New Republic"s Jonathan Cohn, who has been calling attention to potential ways of financing the significant cost of reform, recommends the testimony of Center on Budget and Policy Priorities President Robert Greenstein. Greenstein testified that there are no "painless" ways of raising money for reform, and said, "This leads to my first recommendation, in the form of a plea to the Committee. Please do not take any offset options off the table at this time. I believe you ultimately will need to put together a package that contains an array of spending and revenue offsets." Offsets could include removing or limiting the tax exclusion for employer-sponsored insurance. Bob Lazsewski strenuously disagrees. He illustrates a post titled "Paying for a Big Part of Health Care Reform With New Taxes Would Be a Terrible Mistake!" with a graph of the trends in health insurance premiums over the last 20 years and says, "paying for most of health care reform by raising taxes would be nothing less than cowardly and fiscally irresponsible." He continues, "the Congress is so desperate to find money and so unwilling to anger any powerful health care special interests we better get ready for some interesting rationalizations to promote tax increases in the place of fundamental reforms."After the hearing, ranking member Sen. Mike Enzi (R-Wyo.) gave a presentation at the Heritage Foundation on his preferences for bipartisan reform legislation and the Foundry"s Marguerite Higgins blogged Enzi"s key points. She says the senator wants to increase affordability, use private plans for coverage and ensure a bill is fully paid for.The White House appears to be initiating additional outreach efforts to mobilize support. Jose Antonio Vargas of the Washington Post"s Daily Dose reports that President Obama"s administration chose to send its first WhiteHouse.gov e-mail on health reform Wednesday. Vargas says, "It"s only fitting that Obama"s first official e-mail from the White House is about health care reform. As early as December, the incoming Obama administration began using new media tools to build grassroots support around the issue."Interesting elsewhere:
Britannia Building Society wrapped up its best ever charity fundraising year with a ÷£400,000 birthday boost to Alzheimer"s Society.
Ninety percent of the 5.5 billion kilograms of toxic pollutant releases and transfers reported in North America in 2005 can be traced to just 30 substances from 15 industrial sectors across the United States, Canada and Mexico, according to the latest tri-national pollution report from the Commission for Environmental Cooperation (CEC).
Alexion Pharma France and Alexion Pharmaceuticals, Inc. (NASDAQ: ALXN) today received the 2009 Prix Galien France for Soliris® (eculizumab) in the category of medicines for rare diseases. The award recognizes the scientific innovation represented by the complement-inhibition technology of Soliris, and the impact the drug is having on the lives of patients with paroxysmal nocturnal hemoglobinuria (PNH), an ultra-rare, debilitating and life-threatening blood disorder.
Checkpoint with forkhead and ring finger (CHFR) is a mitotic stress checkpoint gene whose promoter is frequently methylated in various kinds of cancer. In gastric cancer, CHFR promoter hypermethylation has been reported to lead to chromosome instability (CIN) and genetic instability is one of the hallmarks of human cancer.
A quarter of active rheumatoid arthritis (RA) patients receiving either 10mg (24.6%) or 15mg (28.1%) twice daily of the investigational oral JAK-3 (janus-associated kinase) inhibitor CP-690,550 (CP) achieved ACR70* after 12 weeks, according to the results of a new study presented at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark. The primary outcome for the study was ACR20*, with 75.4% of patients achieving this measure at 12 weeks for both 10mg and 15mg doses.
The Arizona AIDS Drug Assistance Program (ADAP) has reduced the number of medications it will cover - antiretrovirals and drugs that treat opportunistic infections will not be affected, the Arizona Daily Star reports. The program relies heavily on federal funding. Judy Norton, chief of the state"s Office of HIV, STD and Hepatitis C Services, said the state received $2.3 million less than what it requested from the federal government, requiring the program to make cuts. According to the Daily Star, federal ADAP funds are "drying up as drug costs rise and as more" people living with HIV/AIDS are enrolling in the program. The Arizona ADAP has been serving about 1,100 patients statewide, although the number has gone up in recent months, Laura Oxley, Arizona Department of Health Services spokesperson, said. A letter explaining the changes to the program was sent to clients and providers earlier this week (Innes, Arizona Daily Star, 6/11).
Zimbabwean Prime Minister Morgan Tsvangirai met with U.S. lawmakers in Washington, D.C., Wednesday in an attempt to secure donations for a country in economic collapse, ZimOnline reports. Tsvangirai"s visit is part of "a three-week trip to America and Europe to try to drum up financial support for the power-sharing government," entered into with his political rival, President Robert Mugabe in February, according to ZimOnline (ZimOnline, 6/11).