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PROLOR Biotech Awarded Two U.S. Patents For Its Longer-Acting Human Growth Hormone And Longer-Acting Erythropoietin
PROLOR Biotech, Inc. (OTC Bulletin Board: PBTH), formerly Modigene Inc., announced that the U. S. Patent and Trademark Office (PTO) has issued two new patents for the company"s long-acting CTP-enhanced human growth hormone (hGH-CTP) and human erythropoietin (EPO-CTP). The patents cover the composition of PROLOR"s proprietary pharmaceutical compounds as well as certain associated methods. PROLOR"s CTP technology is based on a short amino acid sequence, the Carboxyl Terminal Peptide that occurs naturally in humans. When attached to a therapeutic protein, CTP extends the time that the protein is active in the body.
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Income, Education, Important Factors In Heart Disease Risk
Doctors who ignore the socioeconomic status of patients when evaluating their risk for heart disease are missing a crucial element that might result in inadequate treatment, according to a University of Rochester Medical Center study published in the June 2009 American Heart Journal.
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Exelixis Reports Encouraging Phase 1 Data To Be Presented At ASCO For XL228, A Multi-Targeted Inhibitor Of Key Cancer Signaling Kinases
Exelixis, Inc. (Nasdaq: EXEL) today reported encouraging data from an ongoing Phase 1 dose-escalation trial of XL228 in patients with advanced malignancies. XL228 is a small molecule inhibitor of insulin-like growth factor type 1 receptor (IGF1R), SRC, Aurora kinases, and fibroblast growth factor receptor types 1, 2, and 3 (FGFR1-3), which are associated with cancer cell proliferation, survival, and metastasis. The compound also inhibits BCR-ABL, including the T315I mutant form which is resistant to currently approved inhibitors. David Smith, MD, Professor of Medicine at the University of Michigan, an investigator on the Phase 1 trial, will present the data in an oral session (Abstract #3512) beginning at 4:15 p.m. local time on Saturday, May 30, 2009, at the American Society of Clinical Oncology Annual Meeting, which is being held May 29-June 2 in Orlando.

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Canadians Watch U.S. Reform Effort Closely

American health care reform has become a "hot topic north of the border," the Washington Times reports. "If Mr. Obama succeeds, the U.S. could draw even more Canadian doctors and nurses to the U.S., exacerbating a shortage of medical professionals, said Dr. Brian Day, a Canadian health care critic and former head of the Canadian Medical Association. If Mr. Obama fails, perhaps Canada could open its system to "medical tourism" from the U.S., Dr. Day said." Under the Canadian system, everyone is insured and has "access to basic health care without ever seeing a doctor or hospital bill." But 70% of Canadians also have "some form of supplemental health insurance," in part because of long wait times for tests and treatments under the government plan. For Canadian citizens who become ill in the U.S., it is often cheaper to "ride on a private Lear jet back to Canada" than to be treated in a U.S. hospital.

First Anchorage Novel H1N1 confirmed, Alaska

A 28-year-old Anchorage man has become Anchorage"s first confirmed case of the novel H1N1 flu virus. The patient first reported feeling ill on June 1, 2009, and was swabbed for influenza at a clinic on June 3. The sample tested positive for novel H1N1 on June 9.

Antiabortion-Rights Group Operation Rescue Considering Purchase Of Tiller\'s Clinic

Operation Rescue President Troy Newman on Wednesday said that his group is considering trying to purchase murdered abortion provider George Tiller"s Wichita, Kan., clinic, which Tiller"s family permanently closed on Tuesday, the New York Times reports. The clinic is owned by Tiller"s family. The family"s lawyer, Dan Monnat, called Operation Rescue"s proposal "just another irreverent, extremist publicity stunt." He declined to comment further on the situation. The family has not announced its plans for the building and land, which are worth $734,100, according to Sedgwick County, Kan., property records. The clinic has long been a focal point for the antiabortion-rights movement because it was one of the few in the U.S. that offered abortion later in pregnancy. Newman said that he has discussed the possible purchase with only a few members of Operation Rescue"s board but is certain that the funds could be raised if they decide to attempt to buy the clinic. Newman also said that one possibility for the location would be to turn it into a memorial museum to serve as "a tribute to the babies." He denied the claim that his comments are a publicity stunt.According to the Times, the closing of Tiller"s clinic has set off a "flurry of concerns" from abortion-rights advocates that it will be more difficult for women to access abortion services in situations when catastrophic health issues are identified late in pregnancy (Davey, New York Times, 6/11). LeRoy Carhart, a Nebraska abortion provider who worked with Tiller at the clinic, said that he will continue to perform third-trimester abortions in Kansas but did not provide information on where he will practice, the AP/Yahoo! News reports. Although he did not provide details, Carhart said that "there will be a place in Kansas for the later second- and the medically indicated third-trimester patients very soon." He said he has seen an increase in patients at his Nebraska clinic since Tiller"s murder. Carhart traveled to Tiller"s clinic to perform second- and third-trimester abortions because Kansas has less restrictive abortion laws than Nebraska. Carhart said he has not performed any procedures at his clinic after 22 weeks" gestation because his staff is not trained to do them. According to the AP/Yahoo! News, Nebraska law prohibits abortion when a fetus is considered viable. Kansas law, however, allows abortion after 21 weeks" gestation if continuing the pregnancy would endanger the woman"s life or cause "substantial and irreversible impairment" of a major bodily function, which courts have interpreted to include mental health (Gibbs, AP/Yahoo! News, 6/11).Broadcast CoverageThree media outlets on Wednesday reported on issues related to Tiller"s murder. Summaries appear below.~ MSNBC"s "The Rachel Maddow Show": The program included a discussion with Jennifer Boulanger, executive director for the Allentown Women"s Center, about threats to the center since Tiller"s murder (Maddow, "The Rachel Maddow Show," MSNBC, 6/10).~ NPR"s "All Things Considered": The program included a discussion with NPR health policy correspondent Julie Rovner about the correct terminology for referring to abortion later in pregnancy and why the phrase "late-term abortion" is inaccurate (Block, "All Things Considered," NPR, 6/10).~ WBUR"s "On Point": The program included a discussion with the Rev. Katherine Ragsdale -- a board member of NARAL Pro-Choice America and the incoming dean and president of Episcopal Divinity School -- and Jim Wallis -- founder and editor of the progressive evangelical group Sojourners -- about abortion-rights supporters" reaction to violence in the antiabortion-rights movement (Ashbrook, "On Point," WBUR, 6/10).

FDA Recommends Gardasil Recipients Sit, Lie Down After Receiving Vaccination

In a posting aimed at health care professionals, FDA on its Web site on Wednesday said that recipients of Merck"s human papillomavirus vaccine, Gardasil, should be closely observed afterward for 15 minutes while they remain seated or lying down to avoid the possibility of fainting, the Wall Street Journal reports. FDA said that since October 2007, Gardasil"s labeling for both health care providers and patients has included a discussion about fainting. The agency said the strengthened recommendation comes in response to reports of "traumatic injuries" among some recipients who experienced fainting (Corbett Dooren, Wall Street Journal, 6/10). Gardasil protects against the strains of HPV that cause most cases of cervical cancer and genital warts. The Centers for Disease Control and Prevention recommends that girls ages 11 and 12 receive the three-dose vaccine before they are sexually active. Girls and women ages 13 to 26 who have not been vaccinated or completed the vaccine series also should receive the vaccine (CDC fact sheet, June 2008). On Wednesday, FDA also approved changes to Gardasil materials that place warnings about fainting in a more prominent place on drug labels and handouts. The agency said that the new recommendations are intended to "prevent falls and injuries" (Wall Street Journal, 6/10).

First Mosquitoes Test Positive For West Nile Virus In Southern Illinois

Dr. Damon T. Arnold, state public health director, announced a mosquito batch collected in St. Clair County has been confirmed as the first positive West Nile virus test results in southern Illinois this year.

24 New Swine Flu Cases In Mississippi

This week, the Mississippi State Department of Health (MSDH) reported 24 new cases of H1N1 swine flu, bringing the state"s total number of cases to 58. The new cases are in Harrison (7), Jackson (4), Hinds (3), Holmes (2), Rankin (2), Jones (2), Lowndes (2), Lauderdale (1) and Madison (1) counties.

Subclinical Markers Predict Relapse In Juvenile Idiopathic Arthritis Post Methotrexate Withdrawal

Elevated levels of the inflammatory biomarkers Myeloid Related Protein (MRP*) 8/14 predict an increased risk of relapse following withdrawal of methotrexate (MTX) therapy in children with juvenile idiopathic arthritis (JIA) who have achieved inactive disease status, according to a new study presented at PReS 2009, a joint congress with the 2009 Congress of the European League Against Rheumatism (EULAR) in Copenhagen, Denmark.

A Real-Life Example Of Humans\' Dual Vision System

It"s rare when real-world events perfectly mirror experiments that scientists are conducting.

To Promote Cardiovascular Health, Tulane University Partners With South American Universities

Cardiovascular disease researchers at Tulane University are partnering with faculty at the University of Buenos Aires, Argentina, to establish the South American Center of Excellence in Cardiovascular Health. The center has received a five-year, $2.3 million dollar grant from the National Heart, Lung and Blood Institute of the National Institutes of Health.

Nutricia Launches Nutra Neocate, Weaning Product Designed For Cows\' Milk Protein Allergy

Nutricia, the European market leader in advanced medical nutrition, has announced the launch of Neocate Nutra, the first and only weaning product made from 100% non-allergenic amino acids. Neocate Nutra has been specifically developed for weaning infants and older children with cows" milk protein allergy (CMPA) and multiple food protein intolerance (MFPI). Unlike many weaning products, Neocate Nutra contains no hidden allergens and is designed to provide children with the key essential nutrients they need for development. With its unique format, Neocate Nutra is suitable for taking infants through the various stages of weaning and also for older children on very restricted diets who are looking for convenient and varied food options.

Rosiglitazone Does Not Harm Bone Healing If Combined With Metformin In Rats

Taking the diabetes medications metformin and rosiglitazone together reverses the adverse effects on bone of rosiglitazone treatment alone in an experimental model, according to a new study done in rats. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.

Kessler Foundation Research Center Study Provides Insight Into One Of The Most Challenging Symptoms Following A Traumatic Brain Injury

A recent study by Kessler Foundation Research Center published in Brain Injury, the official journal of the International Brain Injury Association, uncovered the possible cause of cognitive fatigue in patients suffering from traumatic brain injury (TBI). Cognitive fatigue has been shown to be one of the most challenging symptoms following TBI, greatly affecting everyday life activities such as work and school. The study also addressed the difficult task of measuring cognitive fatigue through the use of functional MRI (fMRI), an advanced imaging technology. In addition to civilians with TBI, methodology from the study could potentially be used in VA Hospitals to improve the lives of the estimated 300,000 U.S. Iraq and Afghanistan war veterans who suffer from brain injury. Cognitive fatigue is a highly prevalent condition, with 73 percent of TBI patients reporting significant levels of fatigue even five years post-injury.

Medivation Completes Enrollment In Confirmatory, Pivotal Phase 3 \'CONNECTION\' Trial Of Dimebon In Patients With Alzheimer\'s Disease

Medivation, Inc. (Nasdaq: MDVN) announced the completion of patient enrollment in the CONNECTION study, a six-month, confirmatory, pivotal Phase 3 trial of the investigational drug dimebon in patients with mild-to-moderate Alzheimer"s disease.

Senate Bill To Protect Patients\' Healthcare By Amending Medicare Coverage

The U.S. Senate has introduced a bill, S. 1221, "The Medicare Prompt Pay Correction Act," a companion bill to H.R. 1392, which was introduced in the U.S. House of Representatives and currently has 45 co-sponsors.

WHO Raises Pandemic Alert To Phase 6, Director General Gives Speech

The World Health Organization (WHO) announced it has raised the level of influenza pandemic alert from phase 5 to phase 6, following an

Infection Prevention Text Updated, Improved - The APIC Text Of Infection Control And Epidemiology

More than 300 infection prevention experts have completed a text that serves as one of the most valuable tools for infection preventionists throughout the world, the APIC Text of Infection Control and Epidemiology. The 1,700-page document, now in its 3rd edition, has been completely revised and is now available, offering a concise information re containing more than 120 expanded and enhanced chapters.

IDF To Host Clinical And Educational Workshops On Diabetes For Health And Government Officials In Latin America

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Improvements In Prevention And Cardiac Care Mean Fewer Heart Attacks And Fewer Deaths

A new report tracking selected indicators of health system performance over 10 years in Canada shows significant improvements in the prevention and management of heart disease, with fewer Canadians having a heart attack, one of the leading causes of death in this country. Data from the Canadian Institute for Health Information (CIHI) shows the rate of patients admitted to hospital for heart attack in Canada (outside Quebec) dropped 13% between 2003-2004 and 2007-2008, after population growth and aging were taken into account. Over the same time period, deaths in hospital within 30 days of admission for acute myocardial infarction (AMI), or heart attack, were down 11%, and unplanned readmissions to hospital after a heart attack declined by 31%. Health Indicators 2009 marks the 10th anniversary of CIHI"s annual report. Produced with Statistics Canada, the report provides more than 40 comparable measures of health and the health system by health region, province and territory.

Cardiology Experts At Rush University Medical Center Successfully Use Unique Interventional Procedure To Save A Girl With A Very Rare Heart Defect

Seventeen-year-old Sara Abousuiony, who has been homebound since she was an infant, never imagined that she would be able to leave her home in Cairo, Egypt, and travel to the United States for a life-saving heart procedure.

Red Wine Ingredient Demonstrates Significant Health Benefits: Research Review

The benefits of alcohol are all about moderation. Low to moderate drinking - especially of red wine - appears to reduce causes of mortality, while too much drinking causes multiple organ damage.

Jehovah\'s Witnesses Face Increased Risk Of Death During Childbirth

Jehovah"s witnesses are a religious society with more than six million members worldwide. For religious reasons, most Jehovah"s witnesses refuse transfusion of blood or any of its primary components (red and white blood cells, platelets and plasma), even when red blood cell transfusion could be life saving.

HSPH Assistant Professor To Serve As Co-Principal Investigator Of Center In Guatemala To Combat Cardiovascular Disease

Eduardo Villamor , Assistant Professor of International Nutrition at Harvard School of Public Health (HSPH), will serve as co-principal investigator of a research and training center in Guatemala to reduce the burden of cardiovascular disease (CVD) in the Mesoamerican region, which includes Central America, the Caribbean, and Southern Mexico.

Orencia(R) (Abatacept) Demonstrates Consistent Safety And Effectiveness Over 7 Years

Bristol-Myers Squibb Company (NYSE: BMY) announced results of two ORENCIA® (abatacept) studies at the 2009 Annual European Congress of Rheumatology (EULAR) currently being held in Copenhagen, Denmark.

Emerging Health Care Crisis In The Developing World: Gram-Negative Rods Discovered In Two Philippine Neonatal Intensive Care Units

Researchers at Boston University School of Medicine (BUSM) have found a high frequency of multidrug-resistant Gram-negative rods (GNRs) in two of the largest neonatal intensive care units (NICUs) in the city of Manila, Philippines. Improved infection control methods could reduce the vast number of hospital acquired neonatal infections. The BUSM study appears online in the journal Infection Control and Hospital Epidemiology.

Emergent BioSolutions Meets With FDA To Review Regulatory Strategy For Recombinant Anthrax Vaccine

Emergent BioSolutions Inc. (NYSE:EBS) announced that it has met with the U.S. Food and Drug Administration (FDA) to review Emergent"s regulatory strategy for the development of its recombinant anthrax (rPA) vaccine. Emergent recently submitted to FDA, among other documents, its rPA Development Plan in response to the Department of Health and Human Services" (HHS) amendment to its request for proposal (RFP) to develop and deliver up to 25 million doses of an rPA vaccine for the Strategic National Stockpile. In amending the RFP, HHS required that all bidders deemed to be in the competitive range submit to FDA a comprehensive plan outlining the regulatory strategy for their rPA vaccine. Emergent completed that submission on May 12, 2009 ahead of the June 15, 2009 submission deadline.

New Study Demonstrates NanoScan\'s Novel Contrast Agent May Identify Heart Attack In Waiting

NanoScan Imaging, LLC announced the publication of new data demonstrating the use of its investigational, radio-opaque contrast agent (N1177) to visualize vulnerable plaques that can cause heart attack or stroke using advanced, non-invasive and high-resolution computed tomography (CT) techniques. Results of the study were published in the current issue of the peer-reviewed Journal of Nuclear Medicine (J Nucl Med. 2009 Jun;50(6):959-965).

Ardea Biosciences Announces Positive Interim Phase 2a Results For Lead Gout Drug, RDEA594

Ardea Biosciences, Inc. (Nasdaq:RDEA) announced positive interim results from an ongoing Phase 2a, proof-of-concept study of RDEA594, its lead product candidate for the treatment of hyperuricemia and gout, as well as additional positive results from completed Phase 1 studies of RDEA594 in normal, healthy volunteers. The Phase 1 results, along with additional preclinical data, were presented at the Annual European Congress of Rheumatology hosted by the European League Against Rheumatism (EULAR) in Copenhagen, Denmark.

Early Onset Of Prostate Cancer May Be Predicted By Genetic Marker

Fox Chase Cancer Center researchers have identified a genetic marker that is associated with an earlier onset of prostate cancer in Caucasian men who have a family history of prostate cancer. If the data are confirmed, the marker may help clinicians personalize prostate cancer screening.

Hormone May Help Combat Frailty In Older Women

Frail elderly women with unexplained weight loss may benefit from supplementation with the body"s appetite-stimulating hormone, ghrelin, or with similar agents, according to a new study. Results of the study, which was funded partially by the National Institutes of Health, were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.

Unique Study Into Health And Wellbeing Of Older People

A unique Network studying the health and wellbeing of older people is bringing together health, social science and mathematics experts in a revolutionary project which will help shape the long-term provision of health and social care services across the UK and ultimately benefit older people.

Researchers Identify Key Gene In Deadly Inflammatory Breast Cancer

Aggressive, deadly and often misdiagnosed, inflammatory breast cancer (IBC) is the most lethal form of primary breast cancer, often striking women in their prime and causing death within 18 to 24 months. Now, scientists from The Cancer Institute at NYU Langone Medical Center have identified a key gene eIF4G1 that is overexpressed in the majority of cases of IBC, allowing cells to form highly mobile clusters that are responsible for the rapid metastasis that makes IBC such an effective killer.

Vast Majority Won\'t Have Access To Antivirals In Pandemic But Generic Drugs Could Help Prevent Deaths

Almost 90 per cent of the world"s population will not have timely access to affordable supplies of vaccines and antiviral agents in the current influenza pandemic, but it is possible that inexpensive generic drugs that are readily available, even in developing countries, could save millions of lives.

Dose Measurement During Prostate Cancer Treatment

A new PTB measuring system offers the possibility of measuring the absorbed dose in the direct environment of the irradiated tumour

Complications Of Image-Guided Radiofrequency Ablation Of Renal Cell Carcinoma: Causes, Imaging Features And Prevention Methods

UroToday.com - Radiofrequency (RF) ablation of renal cell carcinoma (RCC) has been accepted as a minimally invasive treatment for patients who are not able to undergo surgery1. These patients have such poor medical conditions that they can have a higher risk of postoperative morbidity or mortality compared to the general population.

NeuroLogica Corporation Receives Chinese FDA & CQC Approval To Provide Its CereTom Portable CT Scanner Throughout China

NeuroLogica Corporation, a provider of pioneering portable imaging equipment in CT and SPECT, announced its expansion into the Chinese medical device market with the approval of the company"s life saving CereTom portable CT Scanner by the Chinese State Food and Drug Administration (FDA). The company also announced that it will establish a business liaison office in Beijing.

Industry Groups Increase Lobbying As Details Of Health Plan Emerge

Insurers, business owners, and doctors -- three principal interest groups in health reform -- are stepping up their opposition and lobbying efforts as details of the health plans emerge.

Dartmouth Studies Influence Administration, Even In Choice Of Venue

When President Obama chose Green Bay, Wis., to talk about the need for health reform, he did so in part because the area has achieved a high level of quality, and compared with other parts of the country, succeeded in restraining health care costs, National Public Radio reports. "They"re certainly spending a lot less money, and they are providing care that is equal or better than the care that is provided in many other communities around the country," Elliot Fisher, a researcher at the Dartmouth Institute for Health Policy and Clinical Practice told NPR in an interview. NPR says: "Some of the research the administration is relying on comes from the Dartmouth Institute for Health Policy and Clinical Practice," which focuses on variations in health quality and costs around the country.

Nursing Shortage Eases With Recession\'s Help

"The nation"s deep recession is helping to alleviate the decade-long nursing shortage, as workers who had left the field in better times are returning in droves," the Wall Street Journal reports. The paper quotes a study, one of six papers on the nursing workforce published today in the journal Health Affairs, that found "nearly a quarter-million nurses entered the work force in 2007-08, an 18% surge that was the largest two-year increase in at least three decades." Many of them had left nursing, but "re-entered the work force to compensate for a spouse"s lost income or health benefits, the study said." The increase is "particularly remarkable at a time when the U.S. economy has shed more than six million jobs, helping to solidify the profession"s "recession-proof" image." The study found that the surge in new nurses is due to "efforts to expand nursing schools, attract more young people into the field and improve working conditions," along with an increase in the number of foreign-born nurses.

The New Sports Supplement: Cereal And Milk

Exercise physiologist Lynne Kammer, from The University of Texas at Austin, led a group of researchers who investigated the post-exercise physiological effects of the foods. Kammer and her team studied 12 trained cyclists, 8 male and 4 female. In contrast to many sports nutrition studies, however, the exercise protocol was designed to reflect a typical exercise session. After a warm-up period, the subjects cycled for two hours at a comfortable work rate, rather than the more frequently seen test-to-exhaustion.

Increasing ICS Compliance: The Voice May Be Recorded, But The Results Are Real

Automated phone calling may help physicians solve a perennial problem: patients who don"t take medicine prescribed for chronic health conditions.

CombinatoRx Presents Full Data On Synavive Phase 2 Knee OA Trial At EULAR 2009

CombinatoRx, Incorporated (NASDAQ: CRXX) announced the presentation of full data on Synavive (CRx-102) Phase 2 knee osteoarthritis (OA) trial (COMET-1) at EULAR 2009, the Annual European Congress of Rheumatology in Copenhagen on June 12, 2009. The presentation, "CRx-102, a dissociated glucocorticoid (GC), and prednisolone provide safe and effective pain relief in knee osteoarthritis (OA) in a placebo-controlled Phase 2 trial (COMET-1)", Huttner et.al., describes the full, modified intent-to-treat, safety and efficacy results of Synavive in this clinical trial:

Recipients Of HIV/AIDS Programs Aid Expected To Feel Crunch Of Global Economic Crisis

At the 2009 HIV Implementers" Meeting in Namibia Thursday, Paul DeLay, deputy executive director of UNAIDS, said the global economic crisis will impact countries who receive international aid for HIV/AIDS programs, so recipients of such aid should identify priorities for their programs, the China Post reports (China Post, 6/12).

Progress Seen In Some African HIV/AIDS Prevention, Treatment Programs, U.N. Special Envoy Says At World Economic Forum On Africa

Several African countries have successfully scaled up their HIV/AIDS prevention and treatment programs, U.N. Special Envoy for HIV and AIDS in Africa Elizabeth Mataka said during a media briefing at the World Economic Forum on Africa being held in Cape Town, South Africa, the ZANIS/Lusaka Times reports. Zambia and Botswana were among some of the countries that have made significant progress in southern Africa, according to Mataka.

Pirfenidone May Help Lung Function In IPF Patients According To Large Clinical Trial

A large, well-controlled, multi-national clinical trial program has demonstrated the effectiveness and safety of what may become the first FDA-approved medicine for idiopathic pulmonary fibrosis, or IPF.

Senate GOP Could Use Procedural Tactics To Delay Sotomayor Hearings

Senate Minority Whip Jon Kyl (R-Ariz.), a member of the Senate Judiciary Committee, on Thursday said that the GOP has not ruled out the use of procedural tactics, such as a Republican boycott, to attempt to delay Supreme Court nominee Sonia Sotomayor"s confirmation hearing, Roll Call reports. Republicans have complained that the scheduled July 13 start date for the hearing does not give them enough time to review Sotomayor"s record. Kyl said that Republicans will try to negotiate with Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) for more time if they feel they cannot meet the July 13 deadline (Stanton, Roll Call, 6/11). Leahy said that Sotomayor is entitled to be confirmed on the same timetable as Chief Justice John Roberts, who appeared before the Judiciary Committee less than two months after his nomination (Kivlan, CongressDaily, 6/11).Republican Senate aides say Judiciary Committee ranking member Jeff Sessions (R-Ala.) is not likely to make a final decision for several weeks on whether the GOP will try to delay the nomination. According to Roll Call, Sessions has sought to approach the issue "in a careful, measured way," though he has been critical of some of Sotomayor"s public statements. Roll Call reports that Republicans are apt to display an impartial stance on Sotomayor until the hearing starts, meaning that they likely will delay a decision on whether to stall the nomination until the last minute (Roll Call, 6/11).Sen. Dianne Feinstein (D-Calif.) said that Republican senators are stalling to give conservative groups more time to organize a campaign against Sotomayor that they hope will taint her nomination. Feinstein said that there are "groups out there who need more time for attacks and sound bites." She added, "This is a woman who is qualified, who is brilliant, and who worked her way up" (CongressDaily, 6/11).

Editorial, Opinion Piece Respond To Closure Of Murdered Abortion Provider Tiller\'s Clinic

Two newspapers recently published an editorial and an opinion piece in reaction to the announcement that murdered Kansas abortion provider George Tiller"s Wichita clinic would be permanently closed. The clinic was one of a handful in the U.S. offering abortion procedures in the second and third trimesters. Summaries appear below.~ Kansas City Star: The closing of Tiller"s clinic is "a tragedy for American democracy," and the "irrational violence" of his death has "trumped public policy," a Star editorial states. "The basis of civilization is that we agree to submit to the rule of law in order for society to flourish," the editorial says, adding that Tiller"s murder is "antithetical to that principle. It is dismaying to see a killer achieve his objective." The editorial notes that Tiller provided abortion services in "tragic cases" involving women "at risk of infertility or death; fetuses with severe abnormalities; and victims of rape and incest." It continues that the "reduction or loss of that service will create hardships and may put women"s lives at risk." Hospitals and doctors who refer such cases to abortion providers "must reassess the circumstances under which they would perform late-term abortions," according to the editorial. In addition, the "medical profession must take a role in training and supporting doctors willing to provide abortions," and the government and local police "must do all they can to protect a legal medical practice," the editorial says. It concludes, "Democracy demands that we not allow murder to make de facto public policy" (Kansas City Star, 6/11).~ Eric Zorn, Chicago Tribune: The announcement that Tiller"s clinic will remain permanently closed "was simply more proof that violence and intimidation can get results where civil discourse and political process fail," Tribune columnist Zorn writes. "The question isn"t whether prominent foes of abortion rights are being honest with us when they decry Tiller"s violent death and express regret over the means used to achieve an end they"ve sought," Zorn writes, adding, "Some are, I"m sure." He continues that abortion-rights opponents "recognize that ... a movement calling itself "pro-life"can"t also be pro-murder" and "are politically savvy enough to know that the gains won by terrorist acts are grudging and difficult to sustain." He continues that to "make terrorism less effective, and thereby discourage it," abortion-rights advocates, the medical profession, politicians and law enforcement officials "need to reopen that clinic in Wichita and assure its safe operation ... to defy terrorism, if for no other reason." He concludes that "as long as abortion remains legal, this same coalition needs to strive to expand the number of facilities where it"s available" (Zorn, Chicago Tribune, 6/11).

FDA Requests Labeling Change For Leukotriene Modifiers

The U.S. Food and Drug Administration provided further updated safety information on a class of asthma drugs known as leukotriene modifiers. The FDA has requested that manufacturers include a precaution in the drug prescribing information (drug labeling) regarding neuropsychiatric events (behavior, mood changes) that have been reported in some persons taking montelukast (Singulair), zafirlukast (Accolate), and zileuton (Zyflo and Zyflo CR).

Link Between Sleep And Weight Control

Could sleep be a critical component to maintaining a healthy body weight? According to new research presented on Sunday, May 17, at the American Thoracic Society"s 105th International Conference in San Diego, body mass index (BMI) is linked to length and quality of sleep in a surprisingly consistent fashion.

Breakthrough Swine Flu Test

A leading Melbourne scientist has unveiled a test able to detect Swine Flu, or any other virus, within hours.

Hear! Hear! Texas Wines Fight Cancer Growth

It"s happy hour for Texas wineries.

Crown Censure Of HM Prison Service, UK

The Health and Safety Executive (HSE) has called HM Prison Service to account over a case of Legionnaires Disease at Nottingham Prison.

New Lease Of Life For Vintage Oral Health Posters, UK

The BDA has produced a series of vintage oral health promotional posters and postcards featuring designs produced by the Ministry of Health between the nineteen thirties and sixties. The exclusive series, unveiled at the British Dental Conference and Exhibition, uses a combination of eye-catching vintage illustrations and photographs to emphasise the value of good oral health and nutrition in a fun and novel way.

Dual Role In Breast Tissue For A Protein Involved In Leukemia

A protein known to play a role in growth of some types of leukemia appears to have a mixed function in breast cancer development, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center (GUMC).

What Are Gallstones? What Causes Gallstones?

Gallstones are lumps or stones that develop in the gallbladder or bile duct. Some of the chemicals which exist in the gallbladder, such as cholesterol, calcium bilirubinate, and calcium carbonate, harden into either one large stone or many small ones. According to Medilexicon"s medical dictionary, a gallstone is "A concretion in the gallbladder or a bile duct, composed chiefly of a mixture of cholesterol, calcium bilirubinate, and calcium carbonate, occasionally as a pure stone composed of just one of these substances". An article describes a gallbladder in the bile duct similar to trying to squeeze a golf ball through a straw.

BioElectronics Is Filing For 510(k) Clearance With FDA For Its AllayTM Product

BioElectronics Corp. (PINKSHEETS: BIEL), the maker of inexpensive, disposable drug-free anti-inflammatory devices, announced it is filing an application with the U.S. Food and Drug Administration (FDA) for 510(k) clearance to market its Allay™ Menstrual Pain Relief Patch product. The filing follows a very successful double blinded, placebo controlled clinical trial in which 71% of women in the active group reported either complete elimination or a reduction in their typical menstrual pain symptoms, with 49% showing at least a 50% reduction in pain associated with dysmenorrhea.

Japan\'s Cases Of New H1N1 Flu Surge Over Weekend

The number of confirmed cases of new A/H1N1 swine flu in Japan surged over the weekend, when health officials reported earlier today,

What Is Healthy Eating? What Is A Good Diet?

Healthy eating means consuming the right quantities of foods from all food groups in order to lead a healthy life. Diet is often referred to as some dietary regimen for losing weight. However, diet simply means what food we eat in the course of a 24-hour, one week, or one month, etc. period. A good diet is a nutritional lifestyle that promotes good health. A good diet must include several food groups because one single group cannot provide everything a human needs for good health.

FluoroPharma To Present Phase I Study Results Of Novel Positron Emission Tomography (PET) Myocardial Perfusion Imaging (MPI) Tracer

FluoroPharma Inc., a company developing breakthrough PET molecular imaging agents, announced that it will present Phase I data relating to the safety, dosimetry, and pharmacokinetics in human subjects of BFPET, its novel 18-F labeled PET tracer for myocardial perfusion imaging, at the Society of Nuclear Medicine 2009 Annual Meeting in Toronto.

Clostridium Difficile Infection: Strategic Approaches For Better Outcomes

In recent years, the epidemiology of Clostridium difficile infection (CDI) has been changing. This trend may be the result of antimicrobial use, infection control practices, or other factors. It is critical for healthcare professionals to be aware of the epidemiology of this virulent pathogen and apply evidence-based principles for diagnosis, treatment, and prevention.

Sanofi Pasteur Ready To Support Public Health Efforts In Response To WHO Phase 6 Influenza Pandemic Alert

Sanofi Pasteur, the vaccines division of sanofi-aventis Group (EURONEXT: SAN and NYSE: SNY), announces it is ready to support public health efforts to respond to the emergence of the new A(H1N1) influenza strain following the decision made by the World Health Organization (WHO) to raise the pandemic alert level from Phase 5 to Phase 6, the highest level of alert in the WHO global influenza preparedness plan.

Update On Lu AA21004 Clinical Development Programme In Major Depressive Disorder (MDD)

H. Lundbeck A/S (Lundbeck) and Takeda Pharmaceutical Company Limited (Takeda) jointly announced headline results from the first three clinical trials in the phase III development programme with Lu AA21004 in major depressive disorder (MDD). Previously reported clinical phase II data showed equal efficacy with the 5 and 10 mg doses.

The Genetic Interest Group Welcomes EU Health Ministers\' Move To Tackle Rare Diseases

The Genetic Interest Group, the UK patient organisation for all those affected by genetic disorders,

Going Gluten Free?: The Critical Test Everyone Needs To Have BEFORE They Try The Latest Celebrity Endorsed Diet

Celebrity Elisabeth Hasselbeck is generating a lot of buzz about Gluten-Free living, but International Celiac Expert Shelley Case, RD warns consumers why going gluten-free before being screened for celiac disease can be hazardous to your health!

\'Chronic Underfunding\' Could Hinder Progress In HIV Treatment, Opinion Piece Says

Recent cuts to Arizona"s AIDS Drug Assistance Program and other state services due to "chronic underfunding of HIV services at the state and federal level, the increasing cost of medications and the increasing number of persons living with HIV who lack insurance to pay for these life-saving drugs," will likely reverse the progress made in HIV treatment, J. Kevin Carmichael, an associate medical director at El Rio Community Health Center in Tucson, Ariz., writes in an Arizona Daily Star opinion piece. He continues, "Our legislators need to hear our voices and understand that we cannot accept a shortsighted approach to a fiscal crisis that builds in years of HIV-related illness and guarantees significant future costs" (Carmichael, Arizona Daily Star, 6/15).

AAP President-Elect Testifies Before Senate Committee, Applauds Attention To Children\'s Benefits

The American Academy of Pediatrics (AAP), a non-profit professional organization of

Sen. McConnell Says Filibuster Of Supreme Court Nominee Sotomayor Remains Possible

Appearing on CBS" "Face the Nation" on Sunday, Senate Minority Leader Mitch McConnel (R-Ky.) said that Senate Republicans have not ruled out a filibuster on the Supreme Court nomination of Judge Sonia Sotomayor, The Hill reports. Although McConnell acknowledged that he has "consistently opposed filibustering judges," he added that the "precedent was established" when Democrats filibustered Miguel Estrada, an appeals court nominee under former President George W. Bush. When asked to clarify his statement, McConnell added, "The Democrats have firmly established that as a precedent, but that doesn"t mean you are going to use it" (Blake, The Hill, 6/14). McConnell also said that it is "way too early to be talking about whether or not anybody opposes this nominee" (Schieffer, "Face the Nation," CBS, 6/14).According to The Hill, McConnell is the first top GOP senator to state that a filibuster is a possibility, as most other Republicans have said only that it is too early to determine if it should be an option. Republicans "face a difficult path" if they choose to filibuster Sotomayor because party members have long decried judicial filibusters, The Hill reports (The Hill, 6/14).

SANE Launches Website For Teens In Families Affected By Mental Illness, Australia

SANE Australia launches a new website - itsallright.org - to support the half a million Australian teenagers affected by mental illness in their family.

Heart Charity Calls For The Government To Try Harder On Palliative Care

In response to the House of Commons Public Accounts Committee End of Life Care Report published Ruairi O"Connor, Head of Policy and Public Affairs at the British Heart Foundation (BHF) said:

Gene Evolution Process Discovered

One of the mechanisms governing how our physical features and behavioural traits have evolved over centuries has been discovered by researchers at the University of Leeds.

Novel Discovery In Dendritic Cell Signalling Pathways Pave The Way For New Therapeutic Targets

Scientists from A*STAR"s Singapore Immunology Network (SIgN) and the University of Milano-Bicocca, Italy, have discovered another signaling pathway for the activation and apoptosis, or programmed cell death, of dendritic cells[1] . This discovery was published in the advanced online publication of Nature on 15 Jun 2009.

Inflammatory Molecules Promote Liver Scarring

Scarring of the liver, which can progress to cirrhosis and/or cancer of the liver, is caused by persistent liver damage, such as occurs in those with untreated hepatitis C or alcoholism. Although such scarring (fibrosis) develops in an inflammatory environment, the role of inflammatory molecules has not been well defined. However, a team of researchers at Columbia University, New York, and UCSD, La Jolla, has established that the proteins CCR1 and CCR5 and the soluble inflammatory molecules that bind to them promote the development of liver fibrosis in mice.

Blood-Borne Molecule Helps Regulate Blood-Vessel Integrity

Although maintaining the integrity of blood vessel walls is essential for life, well-controlled temporary leakage of blood contents through the walls of blood vessels into the tissues is a hallmark of inflammation. Although the molecule S1P is known to act on the cells that line blood vessels (endothelial cells) to regulate the permeability of blood vessel walls, the in vivo of SIP in this process remains unknown, and whether it has a role in inflammation has not been determined. In a new study, Shaun Coughlin and colleagues, at UCSF, San Francisco, have shed light on these issues, revealing that mice that lack S1P selectively in plasma (the liquid component of blood) have increased leakage from the blood vessels in response to a variety of stimuli, including inflammatory ones. As the leakage was reversed by treatment with either S1P-containing red blood cells or an agonist for the protein to which SIP binds, the authors conclude that S1P in the blood regulates blood-vessel integrity and prevents potentially lethal decreases in blood volume after exposure to leak-inducing stimuli.

Annals Of Internal Medicine Tip Sheet For June 16, 2009, Issue

Calcium Supplementation Has No Weight-loss Benefit for Obese Patients

All Party Parliamentary Group For Parkinson\'s Disease Announces Report & Parkinson\'s Disease Society Launches Fair Care For Parkinson\'s

When: 8 July 2009 6:00pm - 8:00pm

UCLA Cancer Researchers Develop Model That May Help Identify Lung Cancer Stem Cells

Researchers at UCLA"s Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers.

Merseyside Nurse Jailed For 9 Months For Fraud

A nurse has been sentenced to 9 months" imprisonment at Liverpool Crown Court (15th June, 2009) for obtaining an NHS bursary and then employment in a private nursing home using forged documents, after overstaying his leave to remain in the UK. The conviction follows an investigation by NHS Counter Fraud.

Obesity Charity Launches First Awareness Week

The country"s pre-eminent obesity charity, the National Obesity Forum is staging its first consumer awareness week in November this year.

UNICEF Highlights Child Survival On The Day Of The African Child

Several African countries have made impressive gains in child survival in recent years but much more needs to be done, UNICEF said today in marking the International Day of the African Child. This year"s theme is "Africa Fit for Children: A Call for Accelerated Action Towards Child Survival".

Brits Are Europe\'s Angriest People, Says New Poll But All We Do Is Bite Our Lips, Says British Association Of Anger Management, United Kingdom

A poll commissioned by comedy channel Gold and to be revealed shows that we Britons are the angriest people in Europe, losing our cool on average four times a day and topping even the Italians and French. And what do we believe makes us most angry? Queue jumpers.

Founder Of The Royal Pharmaceutical Society Commemorated In Tunbridge Wells

The 150th anniversary of the death of Jacob Bell, founder of the Royal Pharmaceutical Society of Great Britain, was remembered on Friday 12 June at a ceremony at his memorial in Woodbury Park Cemetery, Royal Tunbridge Wells.

Income, Education, Important Factors In Heart Disease Risk

Doctors who ignore the socioeconomic status of patients when evaluating their risk for heart disease are missing a crucial element that might result in inadequate treatment, according to a University of Rochester Medical Center study published in the June 2009 American Heart Journal.

Preventing Spread Of Infectious Diseases Is Everyone\'s Responsibility

According to a report published recently, we must all share responsibility for preventing the spread of diseases such as swine flu, SARS, avian influenza, diarrhoeal and skin diseases, and even the common cold.

Therapy Helps Improve Outcomes For Patients With Severe Sepsis

A preliminary study suggests that a therapy for severe sepsis or septic shock that included the use of an antibiotic-based "hemoperfusion" device to remove toxic products of bacteria from the blood in addition to conventional treatment resulted in a reduced risk of death and appeared to improve blood circulation and reduce organ dysfunction, according to a report appearing in the June 17 issue of JAMA.

Potential For Noninvasive Brain Tumor Treatment

Duke University engineers have taken a first step toward a minimally invasive treatment of brain tumors by combining chemotherapy with heat administered from the end of a catheter.

Study Gives Clues To Increasing X-Rays\' Power

Three-dimensional, real-time X-ray images of patients could be closer to reality because of research recently completed by scientists at the University of Nebraska-Lincoln and a pair of Russian institutes.

Prostate Cancer Patient Receives First RapidArc Radiotherapy Treatment At Major Danish Hospital

A leading Danish cancer hospital has treated its first patient using RapidArc(R) radiotherapy after installing eight advanced radiotherapy treatment machines from Varian Medical Systems (NYSE: VAR) of Palo Alto, California. Herlev Hospital, to the north-west of Copenhagen, delivered the fast and efficient RapidArc treatment to a prostate cancer patient using a Clinac(R) iX linear accelerator.

Massague: "We Have Discovered The First Genes Intervening In Brain Metastasis"

Joan Massagué (Barcelona, Spain, 1953) is the first winner of the BBVA Foundation Frontiers of Knowledge Awards in the Biomedicine category. The Frontiers of Knowledge Awards are intended to recognize and promote research of excellence. The breadth of disciplines addressed and their monetary amount a combined purse of 3.2 million euros spread over eight prize categories place them among the world"s foremost award schemes.

Histamine Affects Alcohol-related Behaviour

The histamine-3 receptor is important in terms of alcohol-related behaviour, and a drug affecting that receptor may have qualities that alter alcohol-related behaviour. This appears in the study headed by Pertti Panula entitled "Tuberomamillary nucleus neurons, histamine and H3 receptor in hypothalamic regulation of alcohol addiction" which is part of the Substance Use and Addictions research programme of the Academy of Finland.

Disclosing Your Feelings May Help The Course Of Rheumatoid Arthritis: Results From A Randomized Clinical Trial

The health and physiological effects of an intervention which facilitates the opening of feelings are described in a paper published in the current issue of Psychotherapy and Psychosomatics.

May Developmental Experiences Explain "unexplained" Medical Symptoms?

A new theory on the role of developmental experiences is presented in the current issue of Psychotherapy and Psycosomatics.

NHS Trust Focuses On Staff Health

Hydration expert, Water Wellpoint is playing a key role in helping public sector employers look after the health and wellbeing of their staff. The company has recently been working with East London NHS Foundation Trust to run a series of wellbeing days, giving employees the ability to check key aspects of their health in a total voluntary format.

Don\'t Forget Your Condoms At Swansea Pride, Says Terrence Higgins Trust Cymru

HIV and sexual health charity Terrence Higgins Trust (THT) Cymru is reminding visitors to Swansea Pride (Saturday 27th June) not to put their sexual health at risk by getting carried away with the party mood.

Moderates Wooed In House As They Cross Party Lines To Shape Health Legislation

As attempts to gain support for health reform across party lines and from stoic interest groups like the American Medical Association continue, House leaders are seeking to rally centrist members of their own caucus, CQ Politics reports. "House Speaker Nancy Pelosi, whose liberal committee leaders will write health care legislation is attempting to engage moderate Democrats whose votes she will need on the floor."

House Bill May Target Drugmakers\' Advertising Tax Breaks

Rep. Charles Rangel, D-N.Y., says the House Ways and Means Committee may seek to raise money for health reform by imposing a $37 billion tax on drugmaker"s advertisements, Bloomberg reports: "As lawmakers seek ways to pay for a health-care overhaul, "one thing that"s not off the table is you can pick up $37 billion knocking out the deduction for advertising" for prescription drugs,"" Rangel said. The idea is among several proposals by Democratic legislators to raise reform money (Donmoyer, 6/16).

Budget Cuts For Minnesota Health Care Programs, Again

Minnesota Gov. Tim Pawlenty, R-Minn., announced Tuesday that "health and human services will come in for $236 million in additional cuts as part of his unallotment strategy," the Star Tribune reports. The "list of about 20 cuts to health services" includes ending a health care program for the poor "six weeks sooner than expected, saving $15 million" and "reducing hours for personal care attendants, who serve fragile and disabled people." Pawlenty "noted he was proposing no new payment reductions for primary care doctors and clinics, and no additional cuts in Medicaid reimbursements to hospitals that serve a large number of poor patients."

Baylor Health Care System Receives $8M From French Government To Develop HIV Treatment

The French government has awarded Baylor Health Care System with an $8 million grant to develop a therapeutic method of controlling HIV without medication, the Dallas Morning News reports. The funds will go toward establishing an HIV research unit at Baylor"s Institute of Immunology Research, which will focus on researching the immune system cells of people living with HIV (Roberson, Dallas Morning News, 6/17).

"Bunionsň€¦.A Local Study Changes The Standard Of Care."

A recent local study shows a new approach to treating bunions could save up to 400 million dollars a year.

The Lancet Calls For Improvements To Epilepsy Services, UK

Policy makers must increase investment in services to improve the lives of people with epilepsy, according to The Lancet Neurology this month.

Group Health Cooperative Shows Investing In More Primary Care Pays For Itself

An evaluation of recent innovations in delivering primary care at a Group Health Cooperative medical center shows significant success and rapid return on investment. The data led to a decision to invest in these best practices in all of Group Health"s 26 medical centers by 2010.

AARP: Shaheen-Collins Bill Will Keep Americans Healthier And Out Of The Hospital

AARP today proudly endorsed the bipartisan "Medicare

Parkinson\'s Disease Society Joins Forces With Healthy Interactions To Launch New Education Programme

As part of a Europe-wide drive to improve access to information and education for people with Parkinson"s Disease, the Parkinson"s Disease Society (PDS) is launching a new education initiative with American company, Healthy Interactions.

American Medical Association Commits To Help Slow Increases In Health Spending

"The need for health reform that provides coverage and high quality, affordable health care for all Americans is clear. Rising health-care costs strain individual, business and government budgets, and projected increases in health spending are not sustainable. The AMA is committed to action to help achieve greater value from our nation"s health-care spending. We want to help bend the spending curve and move forward on health reform.

Call For \'Radical Overhaul\' Of Funding Of Long-Term Care In The UK

A new model for the funding of long-term care for older people is needed in the UK, delegates at the Actuarial Profession"s Health and Care Conference in Glasgow heard today.

Stanford Medical Center Announces $100,000 Planning Grant For Community Response To Teen Depression And Suicide

Enhancing the response to teen depression and suicide is the focus of a new planning grant announced on June 12 by the Stanford Medical Center. The $100,000 grant, funded by Lucile Packard Children"s Hospital, the Stanford University School of Medicine and Stanford Hospital & Clinics, will support collaboration among Palo Alto-area providers of health care res for teens.

Early Switch From Cyclosporine To Sirolimus After Renal Transplantation Produces Sustained Improvement In Renal Function

BOSTON - Favorable 12-month outcomes are maintained through 30 months of follow-up when renal transplant patients are converted from a cyclosporine (CsA)-based regimen to a sirolimus (SRL)-based regimen three months post-transplant, according to results of the CONCEPT study announced here at the American Transplant Congress (ATC) 2009.

Beating The Radar: Getting A Jump On Storm Prediction

Satellite observation of cloud temperatures may be able to accurately predict severe thunderstorms up to 45 minutes earlier than relying on traditional radar alone, say researchers at the University of Wisconsin-Madison Space Science and Engineering Center.

NIST, DOD, Intelligence Agencies Join Forces To Secure US Cyber Infrastructure

The National Institute of Standards and Technology (NIST), in partnership with the Department of Defense (DOD), the Intelligence Community (IC), and the Committee on National Security Systems (CNSS), has released the first installment of a three-year effort to build a unified information security framework for the entire federal government. Historically, information systems at civilian agencies have operated under different security controls than military and intelligence information systems. This installment is titled NIST Special Publication 800-53, Revision 3, Recommended Security Controls for Federal Information Systems and Organizations.

Enzyme Doesn\'t Act Alone In Atrial Fibrillation

An overactive enzyme is behind a leaky calcium channel that plays a role in the development of atrial fibrillation, which is the most common cardiac arrhythmia that is responsible for a third of all strokes. However, it doesn"t act alone, say researchers at Baylor College of Medicine. The findings can be found online in the current edition of the Journal of Clinical Investigation.

Shape Matters In The Case Of Cobalt Nanoparticles

Shape is turning out to be a particularly important feature of some commercially important nanoparticles - but in subtle ways. New studies* by scientists at the National Institute for Standards and Technology (NIST) show that changing the shape of cobalt nanoparticles from spherical to cubic can fundamentally change their behavior.