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Baxter Announces Findings From Premix Heparin IV Bag Investigation Related To Beebe Medical Center Adverse Event Reports
Today, Baxter is announcing that its investigation of reports from Beebe Medical Center has determined that the three patient events are unrelated to product quality involving the company"s heparin premix products.
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Caring With Confidence
South Essex Partnership University NHS Foundation Trust (SEPT) is hosting an all day event for carers on Wednesday 10th June 2009. The event - You care We care - is taking place at the Towngate Theatre in Basildon and doors will open at 09:30.
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Washington Times Examines Proposed Teen Pregnancy Prevention Initiative In Obama Budget Plan
The Washington Times recently included a two-part series examining President Obama"s proposed reallocation of abstinence-only sex education funding in his 2010 budget plan. The proposal would redirect funding toward a new Teen Pregnancy Prevention Initiative that uses comprehensive sex education curriculums. Summaries of the series appear below.~ Part 1: Obama"s budget proposal states that funds for the Teen Pregnancy Prevention Initiative should go to programs that are proven to help delay first sex, increase contraceptive use or reduce teen pregnancy, though a few advocates of comprehensive sex education say such goals are laudable but too narrow, the Times reports. William Smith -- vice president for public policy for the Sexuality Information and Education Council of the United States -- and James Wagoner -- president of Advocates for Youth -- wrote in a June 17 blog entry that preventing unintended pregnancy among teens is "incredibly important" but that it is "not the only sexual and reproductive health issue facing our nation"s youth." They continued that it would be more beneficial to "expand the scope" of the initiative so it can serve "all young people in all communities, including lesbian, gay, bisexual, transgender and questioning youth, whose needs fall wholly outside of the narrow teen-pregnancy-prevention framework." According to the Times, Smith said in an interview that money allotted for the initiative would be best used if it went to programs focused on "good outcomes" for youth, "not these disaster-aversion silos that don"t serve us well." Wagoner said that advocates have been "very clear in giving the president credit for shifting tracks here in a big way" by ending funding for abstinence-only sex education. However, he added that it is "our job to press for the right destination" and to see the changes implemented into law (Wetzstein, Washington Times, 6/28).~ Part 2: Some supporters of Obama"s proposal argue that it is "exactly the right idea, at the right time," as the U.S. teen birth rate has increased in the last two years after 14 years of decline, the Times reports. Sarah Brown, CEO of the National Campaign To Prevent Teen and Unplanned Pregnancy, said that Obama"s proposal is the "first really focused expenditure on effective teen pregnancy prevention programs." Brown noted that the U.S. has the highest rates of teen pregnancy and birth in the industrialized world. She said that the best programs will address one or more of the three goals of the initiative -- delaying first sex, increasing contraceptive use or reducing teen pregnancy. Last month, about 175 organizations sent a letter to Obama and members of Congress calling for an expanded initiative that would include subjects such as sexually transmitted infections and abusive relationships. However, Brown said that many teen pregnancy prevention programs include discussion of STIs and other areas, "[s]o we really don"t see much tension here" (Wetzstein, Washington Times, 7/5).
Sexual Health

The Development Of Mechanosensitivity

Researchers of the Max DelbrÃøck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have gained crucial insight into how mechanosensitivity arises. By measuring electrical impulses in the sensory neurons of mice, the neurobiologists and pain researchers Dr. Stefan G. Lechner and Professor Gary Lewin were able to directly elucidate, for the first time, the emergence of mechanosensitivity. At the same time they were able to show that neurons develop their sensitivity to touch and pain during different developmental phases but always coincidentally with the growth of the neuronal pathways. (EMBO Journal, 2009, doi:10.1038/emboj.2009.73).* The sensory neurons, which are sensitive to touch and pain, are located in the dorsal root ganglia between the intervertebral discs. The neurons receive the stimulus and convert it into electrical signals that are conveyed to the brain. Signal transduction has been investigated very thoroughly, which has led to the development of drugs that block the transduction of pain signals to the brain. Very little, however, is known about how stimulus sensitivity actually emerges. Using the patch-clamp technique in isolated cells of mouse embryos, the MDC researchers succeeded in measuring tiny electrical currents in the cell membranes after a mechanosensory stimulus. "These measurements are extremely difficult," Dr. Lechner explained, "which is why only very few laboratories in the world are specialized in this area." The researchers in Berlin-Buch were able to show that the sensory neurons in the mouse embryo have already fully developed their mechanosensitivity competence on embryonic day 13. That corresponds to about the end of the sixth month of pregnancy in humans. For this development the neurons do not require any nerve growth factor, which is why the researchers suspect that this process is driven by a genetic program. In contrast, the competence to sense pain in the sensory neurons can only develop with the aid of nerve growth factor (NGF). It takes place at a later stage in embryonic development and even after birth. *Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development Stefan G Lechner, Henning Frenzel1, Rui Wang1 and Gary R Lewin* Department of Neuroscience, Max DelbrÃøck Center for Molecular Medicine, Berlin-Buch, Germany *Corresponding author Barbara Bachtler Helmholtz Association of German Research Centres


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