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Medivation Completes Enrollment In Confirmatory, Pivotal Phase 3 'CONNECTION' Trial Of Dimebon In Patients With Alzheimer's Disease
Medivation, Inc. (Nasdaq: MDVN) announced the completion of patient enrollment in the CONNECTION study, a six-month, confirmatory, pivotal Phase 3 trial of the investigational drug dimebon in patients with mild-to-moderate Alzheimer"s disease.

Identifying High-Risk Patients By Testing Trauma Cases For Blood Alcohol Levels
Too much alcohol often causes trauma, complicates assessment of injury, and interferes with inpatient care. Even though 20 to 37 percent of accident cases in trauma centers are alcohol-related, some trauma patients are reluctant to self report their drinking. A new study has found that testing for alcohol biomarkers - particularly blood alcohol levels (BALs) - can identify high-risk patients admitted to trauma centers who had denied excessive drinking.
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Dual Role In Breast Tissue For A Protein Involved In Leukemia
A protein known to play a role in growth of some types of leukemia appears to have a mixed function in breast cancer development, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center (GUMC).
Cardiovascular

Study Helps To Determine Malaria Susceptibility In Children

Children who were exposed to Plasmodium falciparum "malaria before birth become tolerant to the malaria parasite, or their soluble products," according to a PLoS Medicine study, which has "unravelled the mystery behind why some children are more susceptible to malaria infection and anaemia," ANI/Newstrack India reports. This tolerance, which persists after birth and into childhood, erodes the immune system"s ability to attack and destroy parasites and increases the susceptibility of these children to develop a malaria infection and increases their risk for anemia (7/28). For the study, researchers identified children who had been exposed to P. falciparum malaria in utero from a group of 586 Kenyan newborn babies, according to a Case Western Reserve University press release. "The researchers looked for malaria-specific immune responses in T cells in the newborn babies" cord blood by measuring the production of cytokines, molecules that either activate or inhibit the immune system. Finally, they examined the infants biannually for three years to monitor the children"s immune responses, susceptibility to malaria infection and risk for anemia," according to the release (7/27). According to ANI/Newstrack India, lead researcher, Indu Malhotra, said it is the first time a study has shown why some children are more susceptible to malaria and anemia. She added, "This study is timely given President Obama"s Global Health Initiative to assist developing countries to control malaria, one of the "big three" diseases" (7/28). This information was reprinted from globalhealth.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Global Health Policy Report, search the archives and sign up for email delivery at globalhealth.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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