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Gilead Sciences, Tibotec To Develop Second Once-Daily HIV Treatment
Foster City, Calif.-based Gilead Sciences on Thursday said it has entered into a license and collaboration agreement with Johnson and Johnson subsidiary Tibotec Pharmaceuticals for the development and commercialization of a new once-daily fixed-dose treatment for HIV, the San Francisco Business Times reports. The FDA approved the first once-daily HIV treatment Atripla in 2006 (7/16). The new antiretroviral drug would contain Tibotec"s experimental non-nucleoside reverse transcriptase inhibitor, known as TMC278, and Gilead"s combination pill, Truvada. Kevin Young, head of commercial operations at Gilead "said the new combination pill, along with Gilead"s experimental "quad" pill, will be used for newly-diagnosed patients, with physicians reluctant to change therapy for patients who are responding well to Atripla," Reuters reports. Young said the drug is expected to reach the market in 2011 (Beasley, 7/16).

Controversial Cancer Stem Cells Offer New Direction For Treatment
In a review in Science, a University of Rochester Medical Center researcher sorts out the controversy and promise around a dangerous subtype of cancer cells, known as cancer stem cells, which seem capable of resisting many modern treatments.
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"Bunionṣ€¦.A Local Study Changes The Standard Of Care."
A recent local study shows a new approach to treating bunions could save up to 400 million dollars a year.
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Stanford Medical Center Announces $100,000 Planning Grant For Community Response To Teen Depression And Suicide

Enhancing the response to teen depression and suicide is the focus of a new planning grant announced on June 12 by the Stanford Medical Center. The $100,000 grant, funded by Lucile Packard Children"s Hospital, the Stanford University School of Medicine and Stanford Hospital & Clinics, will support collaboration among Palo Alto-area providers of health care res for teens. "Our community has a wealth of expertise and res in child and adolescent mental health, but no mechanism for a coordinated, timely response to teens in crisis," said Frances Wren, MD. Wren, a pediatric psychiatrist who directs the Child and Adolescent Depression Clinic at Packard Children"s, is partnering with local medical and mental health colleagues to develop a coalition to enhance the health-care response to teen depression. "There is great interest, from all groups treating our community"s youth, in finding ways to work together promptly and effectively to respond to teens in crisis," Wren said. "This grant will help provide the res we need for essential collaboration and planning with all community stakeholders. We hope the new coalition will make a difference in the lives of teens and families." "This is exactly the kind of community need our medical center should respond to," said Christopher Dawes, CEO of Packard Children"s, speaking on behalf of Packard Children"s, Stanford Hospital & Clinics, and the Stanford University School of Medicine. At a meeting last week at Packard Children"s, pediatricians and a panel from the local mental health community identified several key goals for the new coalition. Participants discussed collaboration between primary care and mental health services for teen depression and suicide prevention, pooling of expertise and res, tackling misconceptions and other barriers to mental health treatment. In addition, the coalition hopes to develop a crisis-management protocol for the healthcare response to the community emergency of adolescent suicide, partnering with local families, schools, emergency services, primary care and mental health facilities. "Ninety percent of people who die by suicide are suffering a psychiatric illness such as depression," Wren said. "Fortunately, effective treatments are available for depression and other mental health problems. Our goal is to increase our community"s ability to get these treatments to the young people who need them." Lucile Packard Children"s Hospital Stanford Hospital & Clinics About Stanford University School of Medicine


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