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Experts At Leading Vision Health Care Organization Offer 5 Summer Eye Safety Tips
As summer vacations begin, experts at Lighthouse International urge everyone to take eye safety seriously and prevent damage from the sun that could be permanent. Lighthouse International, based in New York City, is the 104 year old non-profit leader in vision health.
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Editorial, Opinion Piece Respond To Health Care Reform Issues
President Obama is "right to push for [health care] reform now, despite calls to postpone efforts solely on the economic recovery," a Philadelphia Inquirer editorial states. According to the editorial, cost-cutting initiatives proposed by industry groups earlier this week "may not amount to anything" because they are voluntary and "providers" past efforts at containing costs have failed every time." However, the groups" vow to reduce future health care spending by $2 trillion "shows how much fat and waste is in the system," according to the Inquirer. The editorial also states that the "most assured means of tamping down costs while providing greater access to health coverage could be through" a government-run public health insurance option. In addition, Obama "needs to warm to the idea of requiring that all Americans obtain health insurance," in order to spread out the cost of care, the editorial continues. The editorial concludes that "it"s encouraging that Obama doesn"t plan to let a couple of wars and a recession sidetrack him from his pledge to reform health care and expand coverage to all Americans" (Philadelphia Inquirer, 5/14). Opinion Piece
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ARIAD Announces Preliminary Results From Ongoing Clinical Trial Of Its Investigational, Bcr-Abl Inhibitor In Drug-Resistant Chronic Myeloid Leukemia
ARIAD Pharmaceuticals, Inc. (Nasdaq: ARIA) announced preliminary clinical data from an ongoing Phase 1 clinical trial of its investigational, multi-targeted kinase inhibitor, AP24534, in patients with advanced hematological cancers. The study results provide initial clinical evidence of hematologic, cytogenetic and molecular anti-cancer activity of AP24534 in heavily pretreated patients with resistant and refractory chronic myeloid leukemia (CML), including those with the T315I mutant variant of the target protein, Bcr-Abl. An abstract describing these data is being submitted for presentation at a major hematology meeting to be held later this year.
Public Health

Policies On Organ Donation After Cardiac Death Vary Considerably Among Children's Hospitals

Although a large number of children"s hospitals have developed or are developing policies regarding organ donation after cardiac death, there is considerable variation among policies, including the criteria for declaring death, according to a study in the May 13 issue of JAMA. Donation after cardiac death (DCD) potentially permits patients who do not meet the neurological criteria for death to donate solid organs. "Controlled DCD occurs following planned withdrawal of life-sustaining treatment, and uncontrolled DCD occurs after unanticipated cardiac arrest. Potential controlled DCD donors include patients with irreversible catastrophic brain injury or end-stage neuromuscular diseases," the authors write. Although the Joint Commission requires all hospitals to address DCD, little is known about actual hospital policies. Armand H. Matheny Antommaria, M.D., Ph.D., of the University of Utah School of Medicine, Salt Lake City, and colleagues conducted a study to evaluate the development and content of DCD policies at children"s hospitals and evaluate variation among policies, which were collected between November 2007 and January 2008 from hospitals in the United States, Puerto Rico, and Canada. Of inquiries to 124 children"s hospitals, a response was received from 105 (85 percent). Of these respondents, 72 percent had DCD policies, 19 percent were developing policies, and 7 percent neither had nor were developing policies. The researchers received and analyzed 73 approved policies. Sixty-one (84 percent) specify criteria or tests for declaring death, including electrocardiogram (ECG) findings, pulselessness, apnea, and unresponsiveness. Four policies require total waiting periods prior to organ recovery at variance with professional guidelines: 1 less than 2 minutes and 3 longer than 5 minutes. Sixty-four policies (88 percent) preclude transplant personnel from declaring death and 51 percent prohibit them from involvement in premortem (taking place immediately before death) management. While 65 policies (89 percent) indicate the importance of palliative care, only 7 percent recommend or require palliative care consultation. Thirty-two policies (44 percent) preclude the use of medications with the intention to hasten death. Policies differ in the location of withdrawal of life-sustaining treatment. Sixty-eight policies (93 percent) specify the location, with the majority (54 percent) requiring withdrawal of treatment to occur in the operating room. Other potential locations include areas adjacent to the operating room (19 percent), the emergency department (4 percent), or the intensive care unit (4 percent). "This study demonstrates that, consistent with a national emphasis on increasing the supply of transplantable organs, a large number of children"s hospitals have developed or are developing DCD policies," the authors write. "The policies exhibit notable variation both within those we studied and compared with authoritative reports and statements. Further research will be required to determine the importance of variation in the tests for declaring death or the processes for withdrawing life-sustaining treatment. In the long run, public policy may need to address strategies to promote adherence to recommendations for DCD processes based on sufficient clinical evidence and/or ethical justification." JAMA. 2009;301[18]:1902-1908. Journal of the American Medical Association


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