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New Obama Administration Policy To Allow U.S. Asylum For Abused Foreign Women
A recent Obama administration legal filing clears the way for foreign women who have experienced severe domestic beatings and sexual abuse to receive asylum in the U.S., the New York Times reports. The administration stated its position in an April immigration appeals court filing involving a Mexican woman, identified only by her initials, who is seeking asylum in the U.S. because of fear that her abusive common-law husband would kill her. The Times reports that the woman recently consented to having her confidential case documents disclosed to the newspaper.The filing reverses the government"s stance under former President George W. Bush. According to the Times, lawyers say that the Obama administration "has marked a clear, although narrow, pathway for battered women seeking asylum, ... after 13 years of tangled court arguments." Bush administration lawyers had argued as recently as last year that the Mexican woman and others like her could not meet the standards of U.S. asylum law, the Times reports. Applicants for U.S. asylums or refugee status must show a "well-founded fear of persecution" because of race, religion, nationality, political opinion or "membership in a particular social group." The legal debate has been whether women can be included under those terms. According to the Obama administration"s court filing, foreign women who experience abuse would have to prove that their abusers treat them as subordinates and little better than property. They would also have to show that abuse is widely accepted in their country. In addition, they would need to demonstrate that they are unable to find protections from their countries" institutions or by moving somewhere else in their country. The policy does not apply to women fleeing genital mutilation, the Times reports. The Department of Homeland Security has not recommended asylum for the woman. However, DHS senior lawyers wrote in the filing that "it is possible" for her "and other applicants who have experienced domestic violence could qualify for asylum."Under the Clinton administration, Attorney General Janet Reno proposed regulations to clarify the asylum law, but they have never taken effect. DHS lawyers in 2004 raised the possibility of asylum for domestic violence victims, but it was never put into practice in immigration court, according to Karen Musalo, director of the Center for Gender and Refugee Studies at the University of California Hastings College of the Law. "This really opens the door to the protection of women who have suffered these kinds of violations," Musalo said. DHS officials said they now are returning to the 2004 position of stipulating conditions narrow enough to allow domestic violence victims to gain asylum in only a limited number of cases. Matt Chandler, a DHS spokesperson, said, "Although each case is highly fact-dependent and requires scrutiny of the specific threat an applicant faces, the department continues to view domestic violence as a possible basis for asylum in the United States" (Preston, New York Times, 7/16).

Sleep Laboratory Finds Insomnia With Short Sleep Duration Is A Risk Factor For Diabetes
Individuals with insomnia and objective short sleep duration are at increased risk for developing diabetes, according to a research abstract presented at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies.
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School-Based Program Helps Prevent Dating Violence Among Teens, Especially Boys
A school-based program that integrates information about healthy relationships into the existing ninth-grade curriculum appears to reduce adolescent dating violence and increase condom use two and a half years later, according to a report in the August issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. The effects of the low-cost intervention appear stronger in boys.
Cardiovascular

Ovarian Tumor Growth Slowed By Nanoparticle-Delivered 'Suicide' Genes

Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research, a journal of the American Association for Cancer Research. Although early stage ovarian cancer can be treated with a combination of surgery followed by chemotherapy, there are currently no effective treatments for advanced ovarian cancer that has recurred after surgery and primary chemotherapy. Therefore, the majority of treated early stage cancers will relapse. "This report is definitely a reason to hope. We now have a potential new therapy for the treatment of advanced ovarian cancer that has promise for targeting tumor cells and leaving healthy cells healthy," said lead researcher Janet Sawicki, Ph.D., a professor at the Lankenau Institute for Medical Research. Sawicki and colleagues at the Massachusetts Institute of Technology evaluated the therapeutic efficacy of a cationic biodegradable beta-amino ester polymer as a vector for the nanoparticle delivery of a DNA encoding diphtheria toxin suicide gene. These nanoparticles were injected into mice with primary or metastatic ovarian tumors. To test the efficacy of this technique, the researchers measured tumor volume before and after treatment. They found that while treated tumors increased 2-fold, this was significantly less than the between 4.1-fold and 6-fold increase in control mice. Furthermore, four of the treated tumors failed to grow at all, while all control tumors increased in size. Administration of nanoparticles to three different ovarian cancer mouse models prolonged lifespan by nearly four weeks and suppressed tumor growth more effectively, and with minimal non-specific cytotoxicity, than in mice treated with clinically relevant doses of cisplatin and paclitaxel. Edward Sausville, M.D., Ph.D., an associate editor of Cancer Research and associate director for clinical research at the Greenebaum Cancer Center at the University of Maryland, said this report illustrates significant progress in targeted therapy. "In oncology we have been studying ways to kill tumors for a long time, but much of this has run up against the real estate principle of location, location, location," he said. "In other words, an effective therapy is not effective if it cannot get to the target." Sausville said a major accomplishment of this research is the multiple ways it can target ovarian cancer cells, as scientists were able to deliver diphtheria toxin genes, using a nanoparticle, to the actual tumor site (peritoneum) with a basis for selective activity in the cancer cells (how the toxin genes were regulated once inside the cells). "A real plus of a cancer therapy like this is not just the functionality of the nanoparticle construct molecule, but the ability to deliver the toxin to the tumor cells," said Sausville, who agrees that inception of clinical trials could be just 18 months away. Jeremy Moore American Association for Cancer Research


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