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Evaluating The ADHD Medication VYVANSE CII Demonstrated No Change In Pharmacokinetic Profile Of VYVANSE When Coadministered With Prilosec OTC 40 Mg
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced results of a study showing that coadministration of the ADHD medication VYVANSE® (lisdexamfetamine dimesylate) CII with the proton pump inhibitor (PPI) Prilosec OTC® 40 mg (20 mg X 2), did not alter the median time it took for maximum plasma concentration of d-amphetamine to be reached in the subjects evaluated. In the same study, coadministration of Prilosec OTC with ADDERALL XR resulted in a nearly 45 percent reduction in the median time to reach maximum plasma concentrations of amphetamine, the active medication. Other pharmacokinetic parameters (maximum plasma concentration and area under curve) of active medication were not altered for either VYVANSE or ADDERALL XR when coadministered with Prilosec OTC. This study, which is the first to evaluate the pharmacokinetics of VYVANSE and ADDERALL XR taken alone and with Prilosec OTC 40 mg, was recently presented at the International Congress on Clinical Pharmacy, co-sponsored by the American College of Clinical Pharmacy (ACCP), in Orlando, FL.
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Obsessive-Compulsive Disorder Charity Criticise MP Sir Gerald Kaufman, UK

A leading anxiety charity has today criticised Veteran Labour MP Sir Gerald Kaufman for using Obsessive-Compulsive Disorder as an excuse for, by his own admittance "bizarre and daft" MP expense claims. OCD-UK Chief-Executive, Ashley Fulwood commented "Without a doubt OCD can lead to some strange rituals, but there is a huge difference between compulsive habits that everybody has and the debilitating and disabling illness Obsessive Compulsive Disorder. We are not able to comment if Sir Kaufman actually has OCD or not, but regardless we are extremely disappointed that he has used the illness as an excuse in this way which belittles the daily struggles that people affected by OCD go through." Listed amongst the top 10 most debilitating illnesses by the World Health Organisation in terms of loss of income and decreased quality of life Obsessive-Compulsive Disorder is known to impart disabling effects on those affected by this debilitating illness, damaging a person"s overall quality of life, their well being, relationships and careers all suffering because of it. OCD-UK is the leading national charity, independently working with and for people with Obsessive-Compulsive Disorder (OCD). For more information about Obsessive-Compulsive Disorder people visit the OCD-UK website at http://www.ocduk.org OCD-UK


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