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Physical Activity Reduces Prostate Carcinogenesis In A Transgenic Model
UroToday.com - A recent European study demonstrated that 10-year mortality from cardiovascular disease and cancer was decreased in a population of 70 to 90 year olds who adhered to a Mediterranean diet, were physically active, had moderate alcohol consumption and did not smoke. There are also reports suggesting an inverse association between physical activity and risk of prostate cancer (CaP). Yet mechanisms linking lifestyle and longevity are not well investigated. This report in The Prostate investigates an animal model for the association between physical activity and development of CaP.

ImmunoGen Announces Encouraging New Clinical Data With The Company's IMGN901 Compound In The Treatment Of Small-Cell Lung Cancer
ImmunoGen, Inc. (Nasdaq: IMGN), a biopharmaceutical company that develops targeted anticancer therapeutics using its Targeted Antibody Payload (TAP) technology, today announced the presentation of encouraging initial efficacy, safety and tolerability clinical data with its IMGN901 product candidate in the treatment of small-cell lung cancer (SCLC). In two early-stage clinical trials that enrolled patients whose SCLC had recurred following treatment with standard chemotherapies, IMGN901 administration achieved notable tumor shrinkage and/or sustained stable disease. The compound also demonstrated encouraging activity against other CD56-expressing (CD56+) solid tumors. These clinical data are being presented at the 13th World Conference on Lung Cancer taking place in San Francisco, CA, from July 31 to Aug. 4, 2009.
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Research On Food Allergy Triggers: EPA Grant To University Of Chicago
The U.S. Environmental Protection Agency has awarded a $433,100 grant to the University of Chicago to investigate how allergic reactions to food are initiated. The research is expected to lead to improved methods to assess whether pesticides produced in genetically engineered plants can trigger food allergies, which impact more than 11 million Americans each year. The study is funded through EPA"s Science to Achieve Results program (STAR).
Mental Health

New Mass Spectrometric Method Allows Fast And Comprehensive Analysis Of Metabolites

Researchers at the Max Planck Institute for Chemical Ecology in Jena and their colleagues from the Czech Academy of Sciences in Prague have developed a new method to quickly and reliably detect metabolites, such as sugars, fatty acids, amino acids and other organic substances from plant or animal tissue samples. One drop of blood -- less than one micro liter -- is sufficient to identify certain blood related metabolites. The new technique, called MAILD, is based on classical mass spectrometry (MALDI-TOF/MS) and enables researchers to measure a large number of metabolites in biological samples, opening doors for targeted and high-throughput metabolomics. Because of its versatile applications, also in medical diagnostics, the invention is protected by patent. Mass spectrometry is an analytical technique used to elucidate the molecular composition and structure of chemical compounds. In the last two decades mass spectrometry found vast applications in biology, especially for analyzing of large biomolecules. Matrix-Assisted Laser Desorption/Ionization (MALDI), wherein bio-molecules (e.g. proteins) are co-crystallized with a chemical substance called a matrix subsequently irradiated with a laser leads to the formation of protein ions which can be analyzed and detected. However, matrices used in the MALDI technique have a substantial disadvantage: the laser beam not only forms ions from the substances of interest; it also forms low-mass ions (


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