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International Stem Cell Collaboration Results In Discovery Of Promising New Stem Cell Type
DaVinci Biosciences LLC in collaboration with University of Utah, Southern California Center for Regenerative Medicine and Omni Hospital in Ecuador, announce the discovery of a previously unidentified stem cell population from adult human testis in Biochemical and Biophysical Research Communications (BBRC), an international peer-reviewed journal focused on the rapid dissemination of timely and significant experimental results in diverse fields of biological research. Termed gonadal stem cells (GSCs) these adult derived stem cells, unlike previous reported population of stem cells found within the testis, have been found to demonstrate adult stem cell properties. Published in the current journal of Biochemical and Biophysical Research Communications, the data from this collaborative study describes a multipotent adult stem cell population that has the capacity to readily differentiate into multiple cell types. The study evolved from an international collaboration aimed at identifying novel cell populations at different geographical laboratory locations and for different HLA types.

Nanoparticles In Environment Estimated By Novel Approach
Without knowing how much of an industrial chemical is being produced, it is almost impossible for scientists to determine if it poses any threat to the environment or human health.
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Scripps Research Scientists Observe Human Neurodegenerative Disorder In Fruit Flies
A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the United States.
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Is 31P MRS A Useful Tool For Evaluating Early Acute Hepatic Radiation Injury?

Acute hepatic radiation injury could lead to necrosis of hepatocytes, fatty degeneration and hepatic fibrosis. At the present, the gold standard test is liver biopsy. However, this procedure is invasive, uncomfortable for the patients and sometimes results in serious complications. 31P magnetic resonance spectroscopy (MRS) has been used to study liver metabolism in vivo for several years. A research team led by Jian-Shan Mao from Zhejiang University investigated whether changes of 31P MRS in the liver with early acute radiation injury were related to the liver damage score (LDS) and pathologic changes. They also determined the value of 31P MRS in detecting early acute hepatic radiation injury, and identified the most valuable phosphorylated metabolite for detecting acute hepatic injury. Their study was published on June 14, 2009 in the World Journal of Gastroenterology. In this study, 30 rabbits which received different radiation doses (ranging 5-20 Gy) were used to establish acute hepatic injury models. Blood biochemical tests, 31P MRS and pathological examinations were carried out 24 h after irradiation. The degree of injury was evaluated according to LDS and pathology. Ten healthy rabbits served as controls. The MR examination was performed on a 1.5 T imager using a 1H/31P surface coil by the 2D chemical shift imaging technique. The relative quantities of phosphomonoesters (PME), phosphodiesters (PDE), inorganic phosphate (Pi) and adenosine triphosphate (ATP) were measured. They found that there were significant differences of ATP relative quantification among control group, mild injured group, moderate injured group, and severe injured group according to both LDS grading and pathological grading, respectively, and it decreased progressively with the increased degree of injury (r = -0.723, P = 0.000). The relative quantification of PME and Pi decreased significantly in the severe injured group, and the difference between the control group and severe injured group was significant (P Notes: Reference: Yu RS, Hao L, Dong F, Mao JS, Sun JZ, Chen Y, Lin M, Wang ZK, Ding WH. Biochemical metabolic changes assessed by 31P magnetic resonance spectroscopy after radiationinduced hepatic injury in rabbits. World J Gastroenterol 2009; 15(22): 2723-2730 http://www.wjgnet.com/1007-9327/15/2723.asp Correspondence to: Dr. Jian-Shan Mao, Department of Internal Medicine, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China. jshmao@zju.edu.cn Lai-Fu Li World Journal of Gastroenterology


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