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Lexicon's Drug Candidate LX1032 For Carcinoid Syndrome Receives Orphan Drug Designation From EMEA
Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, announced today that it has received orphan drug designation from the Committee for Orphan Medical Products (COMP) of the European Medicines Agency (EMEA) for LX1032, the company"s oral drug candidate for managing gastrointestinal symptoms associated with carcinoid syndrome. LX1032 is designed to reduce serotonin production in patients with metastatic carcinoid tumors. Elevated levels of serotonin contribute to the gastrointestinal and possibly other symptoms experienced by these patients.

Future Of Independent Sector Treatment Centres, UK
The future use of Independent Sector Treatment Centres (ISTCs) in the NHS, will be fairer and on the same terms as other providers of NHS services, Health Minister Mike O"Brien announced today.
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Phase III Study Showed Lucentis Improved Vision In Patients With Branch Retinal Vein Occlusion
Genentech, Inc. announced today that the Phase III study BRAVO showed Lucentis® (ranibizumab injection) improved vision, as measured by the primary endpoint of mean change from baseline in best-corrected visual acuity at six months, in patients with macular edema due to branch retinal vein occlusion. The safety profile of Lucentis was consistent with previous experience and no new adverse events related to Lucentis were observed in the study. Retinal vein occlusion (RVO) is a common cause of vision loss that occurs when blood flow through a retinal vein becomes blocked, such as by a blood clot.
Mental Health

'Green' Fireworks May Brighten Eco-Friendly 4th Of July Displays In Future

With millions of people in the United States eagerly awaiting those July 4 fireworks displays - and our Canadian neighbors doing likewise for their July 1 Canada Day celebrations - here"s a prospect for those light shows of the future likely to ignite a smile on Mother Nature"s face: A new generation of "green" fireworks is quietly making its way toward the sky. That"s "green" as in environmentally friendly. Fireworks, flares and other so-called "pyrotechnics" traditionally have included potassium perchlorate as the oxidizer, a material that provides the oxygen that fireworks need to burn. Perchlorate, however, is an environmental pollutant with potential adverse effects on people and wildlife. Pyrotechnics contain other ingredients, such color-producing heavy metals, with a similar potential. Studies have shown that perchlorate from community fireworks displays conducted over lakes, for instance, can lead to perchlorate contamination of the water. For full details about how perchlorate contaminates lakes after fireworks displays, Click here for a study published in the American Chemical Society"s peer-reviewed journal, Environmental Science & Technology. Researchers, however, have developed new pyrotechnic formulas that replace perchlorate with nitrogen-rich materials or nitrocellulose that burn cleaner and produce less smoke, according to an article in ACS"s weekly newsmagazine, Chemical & Engineering News (C&EN). In the article, C&EN Associate Editor Bethany Halford says these nitrogen-rich formulas also use fewer color-producing chemicals, dramatically cutting down on the amount of heavy metals used and lowering their potentially toxic effects. Some of these fireworks have already been used at circuses, rock concerts and other events, but none have been used at large outdoor displays. The problem: cost. The big challenge in launching these "eco-friendly" pyrotechnics into the sky is making them cost-competitive with conventional fireworks while maintaining their dazzle and glow, the article explains. The article notes that fireworks manufacturers have little incentive to further develop the new green fireworks because no federal regulations currently limit releases of perchlorate from pyrotechnics. Michael Bernstein American Chemical Society


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