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Expert Discusses HIV-Related Kidney Disease, Susceptibility Among Blacks
The New York Daily News profiled Paul Klotman, chair of the Samuel F. Bronfman Department of Medicine at Mount Sinai, who is "one of the world"s leading experts on the kidney diseases associated with HIV." In the article, Klotman discussed the clinical details of HIV-associated nephropathy (HIVAN), including treatment, causes and symptoms. According to the Daily News, doctors estimate that two million to four million people of African heritage have HIVAN, including between 4 percent and 12 percent of blacks with HIV in the U.S. The article continues, "In recent years, doctors have made tremendous advances in their understanding of both HIV and its associated kidney disease." Klotman said, "In thinking about a cure, we know now that we have to clean out the brain and the kidney. Those are things we have to know if we can ever achieve a cure for AIDS" (Charles, 7/22).
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New York Times Editorial Lauds Appointment Of White House Adviser On Violence Against Women
"Domestic violence is a serious law enforcement and public health problem affecting as many as one in four women in this country," but "Washington has devoted too little attention to reducing domestic violence and sexual assaults generally," a New York Times editorial states. The editorial continues, "We welcome President Obama"s decision to create a new post, White House adviser on violence against women, and his appointment" of former National Network To End Domestic Violence Executive Director Lynn Rosenthal, "a seasoned advocate for victims to fill it." According to the editorial, Rosenthal will report to Obama and Vice President Joe Biden, "whose keen interest in the issue dates from his days in the Senate and his key role in enacting the 1994 Violence Against Women Act." The "challenge" facing Rosenthal and the Obama administration "will be to improve the carrying out of existing laws intended to protect women, starting with better coordination of the activities of all the government bureaucracies involved," including the Department of Justice, HHS and the Department of Housing and Urban Development, the editorial states. It notes that a national survey of domestic violence shelters released in May found "a significant increase in the number of women seeking assistance since last fall, a rise largely attributable to the stresses of the economic crisis and rising unemployment." The editorial recommends that states create more emergency shelters, establish more transitional housing for "people fleeing violent situations" and "do more to help these victims rebuild their lives." Rosenthal "will need to tackle bureaucratic and legal hurdles and find more money to help states, localities and charitable groups address those needs," the editorial states. In addition, Rosenthal must "help end the scandal of the thousands of rape kits sitting untested in crime labs and police storage facilities across the country, allowing countless criminals to escape punishment." The editorial concludes, "All of this will require strong and creative leadership" from Rosenthal, Biden and Obama (New York Times, 7/1).
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PolyMedix Receives Regulatory Clearance To Initiate Second Phase I Clinical Study Of Novel Systemic Antibiotic Compound
PolyMedix, Inc., an emerging biotechnology company developing acute care products for infectious diseases and acute cardiovascular disorders, has received a notice of no objection from Health Canada for the Company"s Clinical Trial Application ("CTA") for its defensin mimetic antibiotic compound, PMX-30063. This notice of no objection allows for the initiation of the second human clinical study in Canada. PMX-30063 is a defensin mimetic antibiotic compound, the first of an entirely new class of antibiotic drugs that is believed to work in such a way that makes bacterial resistance unlikely to develop.
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Crown Censure Of HM Prison Service, UK

The Health and Safety Executive (HSE) has called HM Prison Service to account over a case of Legionnaires Disease at Nottingham Prison. An inmate at Nottingham Prison was diagnosed with Legionnaires Disease on 8 March 2006. HSE conducted a thorough and detailed investigation to determine the likely of exposure. High levels of legionella bacteria were discovered in the hot and cold water system in the prison"s Health Unit. HSE found the Approved Code of Practice for controlling legionella bacteria in water systems had not been followed. This was a breach of Section 3 of the Health and Safety at Work etc Act 1974. HM Prison Service attended a formal Crown Censure Hearing at HSE"s Nottingham Office today (12 June 2009). HM Prison Service accepted the Crown Censure after explaining the action it had taken to prevent a recurrence at Nottingham Prison or its other prisons. HSE Director for the Midlands Nick Ratty says the system for managing health and safety at Nottingham Prison had not been effective in controlling this well-known risk. "The standard was far below what is appropriate for a Prison," Mr Ratty said. "This case highlights the need for employers to properly manage hot and cold water systems and manage the risk from legionella bacteria where vulnerable people may be at risk." Notes 1. Section 3(1) of the Health and Safety at Work etc Act 1974 states: "It shall be the duty of every employer to conduct his undertaking in such a way as to ensure, so far as is reasonably practicable, that persons not in his employment who may be affected thereby are not thereby exposed to risks to their health or safety." 2. While the provisions of the Health and Safety at Work etc Act apply to Crown bodies, including departments and agencies, Crown immunity means such bodies are excluded from the provisions for statutory enforcement, including prosecution and penalties. HSE enforces health and safety law in relation to Crown bodies in Great Britain. 3. A list of censured Crown Bodies is published online and in the HSE annual report. 4. Cabinet Office Personnel Information Note 45 (PIN 45), which deals with the enforcement procedures for Crown bodies, including Crown censures, can be found on HSE"s website at: http://www.hse.gov.uk/foi/internalops/sectors/public/7_01_34.pdf 5. Legionnaires Disease is a potentially fatal form of pneumonia caused by bacteria found naturally in environmental water s, but can pose a risk to public health in certain circumstances where the conditions are right. There is more information available online at http://www.hse.gov.uk/legionnaires HSE


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