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Yeast Missing Sex Genes Undergo Unexpected Sexual Reproduction
An emerging form of the pathogenic yeast Candida is able to complete a full sexual cycle in a test tube, even though it"s missing the genes for reproduction. And it may also do so while infecting us, according to Duke University Medical Center researchers.
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Hormone May Help Combat Frailty In Older Women
Frail elderly women with unexplained weight loss may benefit from supplementation with the body"s appetite-stimulating hormone, ghrelin, or with similar agents, according to a new study. Results of the study, which was funded partially by the National Institutes of Health, were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
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Efficacy Of Tecarfarin Mirrors Earlier Studies While Primary Endpoint Missed
ARYx Therapeutics, Inc. (NASDAQ:ARYX), a biopharmaceutical company, announced results from its Phase 2/3 clinical trial, EmbraceAC, comparing its novel anticoagulant agent tecarfarin (previously ATI-5923) with the leading oral anticoagulant warfarin. In this trial, tecarfarin demonstrated efficacy essentially the same as in earlier Phase 2 studies but did not achieve the primary endpoint of superiority over warfarin, as measured by time in therapeutic range (TTR). This was due to the virtually unprecedented performance of warfarin in this trial. Using the International Normalized Ratio (INR), which is the standard measure of anticoagulation to evaluate TTR, the patients in the trial who were administered tecarfarin stayed within the target therapeutic range 74.0% of the time treated as compared to those patients receiving warfarin who stayed within the target therapeutic range 73.2% of the time (p=0.506). The result for the warfarin group was unexpected based upon the extensive history of prior studies and published literature for the drug. Tecarfarin appeared to be well tolerated by the patients in this Phase 2/3 clinical trial.
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Bausch & Lomb Vision Care Strengthens Its Commitment To ReNu® Brand And The Eye Care Community

Bausch & Lomb Vision Care announces a renewed focus on its ReNu® brand of lens care solutions through a U.S. consumer need-based rebranding effort that introduces eye care practitioners and consumers to ReNu® Fresh Lens Comfort™ and ReNu® Sensitive Eyes®. Additionally, the company has recently established a dedicated U.S. lens care solution and eye care product sales force that is primarily responsible for engaging with eye care practitioners and keeping them updated on the benefits of Bausch & Lomb products for their patients and their practice. "We felt that it was time to rejuvenate our original ReNu® brand of lens care solutions through a consumer need-driven portfolio approach that clearly articulates the specific benefits of each formula," says Steven Robins, president, North America, Vision Care. "With ReNu® Fresh Lens Comfort™ and ReNu® Sensitive Eyes®, we can more directly help meet existing consumer needs such as the desire for a fresh lens feeling daily or for a solution that is gentle enough for sensitive eyes." To support its renewed commitment to lens care solutions and other eye care products, Bausch & Lomb has also established a dedicated U.S. sales force known as the Eye Care Specialist (ECS) team. Tasked with reaching out to the medical community and driving engagement, the ECS team is currently focusing on reaching eye care practitioners in the eastern half of the U.S. The program may also expand to the western half of the country next year. One of the team"s first tasks is to introduce eye care practitioners to the rebranding of the ReNu® portfolio. ReNu® Fresh Lens Comfort™, formerly ReNu MultiPlus®, is specifically designed to keep contact lenses feeling like a fresh pair every day. The formula is the only multi-purpose solution on the market with Hydranate®, a clinically-tested ingredient that removes protein deposits that accumulate during wear. It also contains poloxamine to help remove dirt and debris and enhance wettability and moisture retention for a more comfortable feeling throughout the day, as well as DYMED®, which provides unsurpassed disinfection efficacy. Additionally, as part of its new consumer needs-based portfolio strategy, Bausch & Lomb has repositioned its ReNu® Multi-Purpose Solution as ReNu® Sensitive Eyes®. Available in new packaging at stores nationwide in July 2009, this multi-purpose solution is designed specifically for lens wearers who want a gentle formula. "A number of contact lens wearers identify themselves as having sensitive eyes," says Robins. "We wanted to take into consideration this consumer need by letting them know that we have a formula on shelves that has sensitive eyes in mind from the very beginning." Proven to help provide gentle lens care for soft contact lenses, ReNu® Sensitive Eyes® features fewer ingredients and is intended to provide gentle cleaning without sacrificing performance and a high level of disinfection for healthy lens wear. It is specifically formulated to gently draw teardrops to the lenses and create a moisturizing comfort that results in less burning, stinging and irritation for the wearer. The suggested rub regimen also helps to remove potentially irritating particles. Bausch & Lomb


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