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Can-Fite BioPharma To Initiate Phase I/II Clinical Trial With CF102 For The Treatment Of Hepatitis C Virus
Can-Fite BioPharma (TASE:CFBI), a biotechnology company traded on the Tel Aviv Stock Exchange announced that, following the approval by the Israel Ministry of Health and Rabin MC Ethics Committee, a phase I/II clinical trial with CF102 for the treatment of HCV will now start enrolling patients.
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HIV Prevention Efforts In Five African Countries Not Reaching At-Risk Groups, Report Says
National HIV prevention strategies in at least five African countries are not reaching the groups most at risk of infection, according to a report from UNAIDS and the World Bank conducted in conjunction with the national HIV/AIDS authorities of Kenya, Lesotho, Mozambique, Swaziland and Uganda, IRIN/PlusNews reports. The study was conducted between 2007 and 2008 to determine how and where most HIV cases were occurring in each country. It also aimed to examine whether prevention programs and spending aligned with those findings. According to the report, most prevention initiatives are not based on evidence of the behaviors that spread HIV in the five surveyed countries. For example, most new infections in Lesotho occur because of concurrent sexual partnerships, both before and after marriage. However, the country does not have any prevention strategies aimed at concurrent partnerships, or couples who are married or in long-term relationships. In addition, the report found that in Mozambique, an estimated 19% of new HIV infections were spread through commercial sex work, 3% from injection drug use and 5% among men who have sex with men. According to the report, few programs in the country target sex workers, while none are tailored to IDUs or MSM. According to the report, spending on HIV prevention often is low in the surveyed countries. Lesotho spends 13% of its national HIV/AIDS budget on prevention, while Uganda spends 34%. Director of the World Bank"s Global HIV/AIDS Unit Debrework Zewdie said that the economic downturn makes it important to maximize the impact of HIV prevention investments. "These syntheses use the growing amounts of data and information available to better understand each country"s epidemic and response and identify how prevention might be more effective," she said. The report includes recommendations on how the surveyed countries can better implement evidence-based prevention efforts. It said that Lesotho should revise its prevention messages to address multiple concurrent partnerships and integrate the subject into future initiatives. In addition, Mozambique should focus condom promotion on groups such as sex workers, the report said. According to IRIN/PlusNews, the five-country program aims to enhance capacity to ensure that the countries can conduct similar studies in the future (IRIN/PlusNews, 5/27).
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Gene Variations Can Be Barometer Of Behavior, Choices
Researchers at Brown University and the University of Arizona have determined that variations of three different genes in the brain (called single-nucleotide polymorphisms) may help predict a person"s tendency to make certain choices.
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A Selection Of Recent Studies And Surveys

National Cancer Institute: Racial Disparities in Breast Cancer Mortality Are Not Driven by Estrogen Receptor Status Alone -- "Black women who are diagnosed with breast cancer have a higher probability of dying from the disease than white women, regardless of their estrogen receptor status," a study published online in the Journal of the National Cancer Institute finds, according to a NCI description of the document. By comparing the breast cancer rates for black and white women using data from the NCI"s Surveillance, Epidemiology and End Result (SEER) program, researchers found that the "differences in breast cancer mortality may reflect racial differences in access and response to innovative breast cancer treatments, as well as other biological and non-biological factors" and "differences in outcomes in the first few years post-diagnosis make up nearly all of the disparity" (7/7). New England Journal of Medicine: The Effect of Medicare Part D on Drug and Medical Spending -- "[Medicare] Part D increased the use of prescription drugs among enrollees who previously had either no drug coverage or modest benefits and that the cost of the increased use was approximately offset by decreases in other medical spending," conclude the authors of a recent study. The findings are based on a comparison between the money spent on "prescription drugs and other medical care 2 years before the implementation of Part D in January 2006 with such expenditures 2 years after the program"s implementation in four groups of elderly beneficiaries: Medicare Advantage enrollees with stable, uncapped, employer-based drug coverage throughout the study period (no-cap group), those who had no previous drug coverage, and those who had previous limited benefits (with either a $150 or a $350 quarterly cap) before they were covered by Part D in 2006" (7/2). Health Affairs: How Well Did Health Departments Communicate About Risk At The Start Of The Swine Flu Epidemic In 2009? -- This paper examines how quickly state and local health departments were able to react to the declaration that H1N1 influenza (swine flu) was a public emergency by the secretary of HHS on April 26, 2009, as measured through the ability of the departments to "provide online information to their constituents within twenty-four hours of the declaration." The analysis revealed, "[t]he overwhelming majority of state health departments, and more than half of health departments participating in the Cities Readiness Initiative" - a federally funded program aimed at increasing the ability of cities to deliver medicines and medical supplies in a public emergency - "were successful" at meeting the 24-hour goal, compared to "only a quarter of smaller, local health departments" (7/7). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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